Tanaka T, Kondou K, Kouno I
School of Pharmaceutical Sciences, Nagasaki University, Japan.
Phytochemistry. 2000 Jan;53(2):311-6. doi: 10.1016/s0031-9422(99)00533-6.
To examine the metabolism of proanthocyanidins in banana fruit, (-)-epigallocatechin was treated with the homogenate of the fruit flesh to yield (-)-gallocatechin and an oxidation product, 1-(3,4,5-trihydroxyphenyl)-3-(2,4,6-trihydroxyphenyl)-2-hydroxy-1-propan one. The latter product is a stable form of a key intermediate in the oxidative metabolism of flavan-3-ols, and is also related to the biogenesis of A-type proanthocyanidins. In addition, treatment of the reaction mixture with o-phenylenediamine afforded monomeric and dimeric phenazine derivatives generated by condensation with the o-quinone form of the oxidation product.
为研究香蕉果实中原花青素的代谢，用果肉匀浆处理（-）-表儿茶素，生成（-）-没食子儿茶素和一种氧化产物1-（3,4,5-三羟基苯基）-3-（2,4,6-三羟基苯基）-2-羟基-1-丙酮。后一种产物是黄烷-3-醇氧化代谢中关键中间体的稳定形式，也与A型原花青素的生物合成有关。此外，用邻苯二胺处理反应混合物，得到了由氧化产物的邻醌形式缩合生成的单体和二聚体吩嗪衍生物。
