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生物电阻抗分析在评估持续性非卧床腹膜透析患者营养状况中的应用

Bioelectrical impedance analysis in the evaluation of the nutritional status of continuous ambulatory peritoneal dialysis patients.

作者信息

Passadakis P, Sud K, Dutta A, Singhal M, Pettit J, Chatalalsingh C, Thodis E, Vargemezis V, Oreopoulos D

机构信息

General Hospital of Alexandroupolis, Greece.

出版信息

Adv Perit Dial. 1999;15:147-52.

PMID:10682091
Abstract

The authors evaluated the nutritional status of 47 continuous ambulatory peritoneal dialysis (CAPD) patients, 26 men (age 58.9 +/- 14.6 years, duration on CAPD 27.3 +/- 18.3 months) and 21 women (age 56.2 +/- 14.9 years, duration on CAPD 34.5 +/- 23.4 months), using subjective global assessment (SGA), an established method for the nutritional assessment of dialysis patients, and bioelectrical impedance analysis (BIA: body cell mass, fat mass, and phase angle). Of the studied patients, 19 were diabetic (age 59.7 +/- 13.8 years, duration on CAPD 29.2 +/- 19.7 months) and 28 were non diabetic (age 53.9 +/- 14.3 years, duration on CAPD 31.5 +/- 21.8 months. According to SGA, 24 patients were scored as well nourished (Group I), 18 as mildly malnourished (Group II), and 5 as moderately malnourished (Group III). No patient scored as severely malnourished (Group IV). Analysis of the main nutritional parameters for the subgroups revealed a proportional decrease in phase angle, with a statistically significant correlation (p < 0.009) between phase angle and SGA. No significant difference was seen in serum albumin levels between patients in Group I and Group II, but the mean level was significantly lower in patients in Group III compared to Group I. The nutritional and biochemical data in diabetic patients and non diabetic patients were not significantly different. BIA phase angle seems to be a simple and reliable method for the routine assessment of nutritional status in CAPD patients.

摘要

作者使用主观全面评定法(SGA,一种已确立的用于评估透析患者营养状况的方法)和生物电阻抗分析(BIA:体细胞质量、脂肪量和相位角),对47例持续性非卧床腹膜透析(CAPD)患者的营养状况进行了评估。这些患者中,26例男性(年龄58.9±14.6岁,CAPD治疗时间27.3±18.3个月),21例女性(年龄56.2±14.9岁,CAPD治疗时间34.5±23.4个月)。在研究的患者中,19例为糖尿病患者(年龄59.7±13.8岁,CAPD治疗时间29.2±19.7个月),28例为非糖尿病患者(年龄53.9±14.3岁,CAPD治疗时间31.5±21.8个月)。根据SGA评定,24例患者营养状况良好(第一组),18例为轻度营养不良(第二组),5例为中度营养不良(第三组)。没有患者评定为重度营养不良(第四组)。对各亚组主要营养参数的分析显示,相位角呈比例下降,相位角与SGA之间存在统计学显著相关性(p<0.009)。第一组和第二组患者的血清白蛋白水平无显著差异,但第三组患者的平均水平与第一组相比显著降低。糖尿病患者和非糖尿病患者的营养及生化数据无显著差异。BIA相位角似乎是一种用于常规评估CAPD患者营养状况的简单可靠方法。

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