• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

急性病老年患者住院前的功能状态:回顾性报告的有效性及临床重要性

Functional status before hospitalization in acutely ill older adults: validity and clinical importance of retrospective reports.

作者信息

Covinsky K E, Palmer R M, Counsell S R, Pine Z M, Walter L C, Chren M M

机构信息

Department of Dermatology, The University of California, San Francisco and The San Francisco Veterans Affairs Medical Center, USA.

出版信息

J Am Geriatr Soc. 2000 Feb;48(2):164-9. doi: 10.1111/j.1532-5415.2000.tb03907.x.

DOI:10.1111/j.1532-5415.2000.tb03907.x
PMID:10682945
Abstract

OBJECTIVES

Retrospective reports of patients' functional status before hospital admission are often used in longitudinal studies and by clinicians caring for hospitalized patients. However, the validity of these reports has not been established. Our aim was to examine the validity of retrospective reports by testing hypotheses about the relationships these measures would have with other clinical measures if they were valid.

DESIGN

A prospective cohort study.

PARTICIPANTS AND SETTING

A total of 2877 older patients (mean age 81, 36% women) hospitalized on the general medical service at two hospitals. For 1953 of the subjects, the patient was the primary respondent, whereas for 924 subjects, a surrogate was the primary respondent.

MEASUREMENTS

Shortly after hospital admission, patients or surrogates reported whether the patient was independent in each of five activities of daily living (ADLs) on admission and at baseline 2 weeks before admission. Outcome measures included reported independence in each ADL 3 months after the hospitalization and survival to 1 year.

RESULTS

Patients' retrospective reports of their ADL function 2 weeks before admission had a clinically plausible relationship with ADL function at the time of admission, in that patients independent in an ADL on admission rarely reported they were dependent in that ADL 2 weeks before admission (range 2-6%). Surrogates were somewhat more likely than patients to report that patients independent on admission were dependent 2 weeks before admission (range 5-14%). Retrospective reports of prehospitalization ADL function demonstrated strong evidence of predictive validity for both patients' and surrogates' reports. For example, among patients dependent in bathing on admission, patients who were reported as independent 2 weeks before admission were much more likely than those reported as dependent 2 weeks before admission to be independent 3 months after hospitalization (68% vs 20%, P < .001 for patient respondents; 30% vs 5%, P < .001 for surrogate respondents). Similarly, among patients dependent in bathing on hospital admission, survival 1 year after hospitalization was much higher in patients who were independent in bathing 2 weeks before admission than patients who were dependent 2 weeks before admission (76% vs 59%, P < .001 for patient respondents; 60% vs 45%, P < .001 for surrogate respondents). Results were similar for each of the other four ADLs. In a logistic regression model controlling for the number of ADLs reported as dependent on admission, the number of ADLs reported as dependent 2 weeks before admission was significantly associated with 1-year mortality among both patient (odds ratio (OR) = 1.39 per dependent ADL, 95% confidence interval (CI) - 1.26-1.54) and surrogate (OR = 1.14, 95% CI = 1.06-1.24) respondents.

CONCLUSIONS

Hospitalized patients' assessments of their ability to perform ADLs before their hospitalization have evidence of face and predictive validity. These measures are strong predictors of important health outcomes such as functioning and survival. In particular, among patients dependent in ADL function on hospital admission, these results highlight the prognostic importance of inquiring about the patient's functional status before the onset of the acute illness.

摘要

目的

患者入院前功能状态的回顾性报告常用于纵向研究以及照顾住院患者的临床医生。然而,这些报告的有效性尚未得到证实。我们的目的是通过检验关于这些测量指标若有效则与其他临床指标之间关系的假设,来检验回顾性报告的有效性。

设计

一项前瞻性队列研究。

参与者与研究地点

两家医院普通内科病房共收治了2877例老年患者(平均年龄81岁,36%为女性)。其中1953例患者由本人作为主要应答者,而924例患者由代理人作为主要应答者。

测量指标

入院后不久,患者或代理人报告患者入院时及入院前2周基线时在五项日常生活活动(ADL)中的每项活动是否独立。结局指标包括住院3个月后报告的每项ADL的独立性以及1年生存率。

结果

患者对入院前2周ADL功能的回顾性报告与入院时的ADL功能具有临床上合理的关系,即入院时某项ADL独立的患者很少报告入院前2周在该项ADL中依赖(范围为2% - 6%)。代理人比患者更有可能报告入院时独立的患者在入院前2周依赖(范围为5% - 14%)。入院前ADL功能的回顾性报告显示出对患者和代理人报告都有预测有效性的有力证据。例如,在入院时依赖洗澡的患者中,报告入院前2周独立的患者在住院3个月后独立的可能性远高于报告入院前2周依赖的患者(患者应答者中为68%对20%,P <.001;代理人应答者中为30%对5%,P <.001)。同样,在入院时依赖洗澡的患者中,入院前2周洗澡独立的患者住院1年后的生存率远高于入院前2周依赖的患者(患者应答者中为76%对59%,P <.001;代理人应答者中为60%对45%,P <.001)。其他四项ADL中的每项结果均相似。在一个控制了入院时报告为依赖的ADL数量的逻辑回归模型中,入院前2周报告为依赖的ADL数量与患者(比值比(OR)=每个依赖ADL为1.39,95%置信区间(CI) - 1.26 - 1.54)和代理人(OR = 1.14,95% CI = 1.06 - 1.24)应答者的1年死亡率均显著相关。

结论

住院患者对其住院前进行ADL能力的评估具有表面效度和预测效度的证据。这些测量指标是功能和生存等重要健康结局的有力预测指标。特别是,在入院时依赖ADL功能的患者中,这些结果突出了在急性疾病发作前询问患者功能状态的预后重要性。

相似文献

1
Functional status before hospitalization in acutely ill older adults: validity and clinical importance of retrospective reports.急性病老年患者住院前的功能状态:回顾性报告的有效性及临床重要性
J Am Geriatr Soc. 2000 Feb;48(2):164-9. doi: 10.1111/j.1532-5415.2000.tb03907.x.
2
Measuring prognosis and case mix in hospitalized elders. The importance of functional status.评估住院老年人的预后和病例组合。功能状态的重要性。
J Gen Intern Med. 1997 Apr;12(4):203-8. doi: 10.1046/j.1525-1497.1997.012004203.x.
3
Loss of independence in activities of daily living in older adults hospitalized with medical illnesses: increased vulnerability with age.因内科疾病住院的老年人日常生活活动能力丧失:随着年龄增长易感性增加。
J Am Geriatr Soc. 2003 Apr;51(4):451-8. doi: 10.1046/j.1532-5415.2003.51152.x.
4
Relation between symptoms of depression and health status outcomes in acutely ill hospitalized older persons.急性病住院老年人抑郁症状与健康状况结局之间的关系。
Ann Intern Med. 1997 Mar 15;126(6):417-25. doi: 10.7326/0003-4819-126-6-199703150-00001.
5
Unsteadiness reported by older hospitalized patients predicts functional decline.老年住院患者报告的身体不稳预示着功能衰退。
J Am Geriatr Soc. 2003 May;51(5):621-6. doi: 10.1034/j.1600-0579.2003.00205.x.
6
Hospitalization and development of dependence in activities of daily living in a cohort of disabled older women: the Women's Health and Aging Study I.一组残疾老年女性的住院情况及日常生活活动能力依赖的发展:女性健康与衰老研究I
J Gerontol A Biol Sci Med Sci. 2005 Jul;60(7):888-93. doi: 10.1093/gerona/60.7.888.
7
Association of Functional Impairment in Middle Age With Hospitalization, Nursing Home Admission, and Death.中年时期的功能障碍与住院、入住养老院和死亡的关联。
JAMA Intern Med. 2019 May 1;179(5):668-675. doi: 10.1001/jamainternmed.2019.0008.
8
Predicting functional status outcomes in hospitalized patients aged 80 years and older.预测80岁及以上住院患者的功能状态结局。
J Am Geriatr Soc. 2000 May;48(S1):S6-15. doi: 10.1111/j.1532-5415.2000.tb03142.x.
9
The role of functional status in discharge to assisted care facilities and in-hospital death among dialysis patients.透析患者的功能状态对转入辅助护理机构和院内死亡的影响。
Am J Kidney Dis. 2011 Nov;58(5):804-12. doi: 10.1053/j.ajkd.2011.06.017. Epub 2011 Aug 5.
10
Hospital admission risk profile (HARP): identifying older patients at risk for functional decline following acute medical illness and hospitalization.医院入院风险评估(HARP):识别急性疾病和住院后有功能衰退风险的老年患者。
J Am Geriatr Soc. 1996 Mar;44(3):251-7. doi: 10.1111/j.1532-5415.1996.tb00910.x.

引用本文的文献

1
Functional Trajectories After COVID-19 Hospitalization Among Older Adults.老年人新冠病毒感染住院后的功能轨迹
J Am Geriatr Soc. 2025 Jun;73(6):1733-1741. doi: 10.1111/jgs.19420. Epub 2025 Mar 17.
2
In-Hospital Delirium and Disability and Cognitive Impairment After COVID-19 Hospitalization.COVID-19 住院后院内谵妄与残疾和认知障碍。
JAMA Netw Open. 2024 Jul 1;7(7):e2419640. doi: 10.1001/jamanetworkopen.2024.19640.
3
Inactivity May Identify Older Intensive Care Unit Survivors at Risk for Post-Intensive Care Syndrome.
不活动可能会识别出老年重症监护病房幸存者患有重症监护后综合征的风险。
Am J Crit Care. 2024 Mar 1;33(2):95-104. doi: 10.4037/ajcc2024785.
4
Associations Between Inactivity and Cognitive Function in Older Intensive Care Unit Survivors.活动不足与老年重症监护病房幸存者认知功能的关系。
Dimens Crit Care Nurs. 2024;43(1):13-20. doi: 10.1097/DCC.0000000000000613.
5
Assessment tools and incidence of hospital-associated disability in older adults: a rapid systematic review.评估工具与老年人医院相关性失能的发生率:快速系统评价。
PeerJ. 2023 Oct 19;11:e16036. doi: 10.7717/peerj.16036. eCollection 2023.
6
SPICT as a predictive tool for risk of 1-year health degradation and death in older patients admitted to the emergency department: a bicentric cohort study in Belgium.SPICT 作为预测工具,用于预测急诊科老年患者 1 年内健康恶化和死亡的风险:比利时的一项双中心队列研究。
BMC Palliat Care. 2023 Jun 24;22(1):79. doi: 10.1186/s12904-023-01201-9.
7
Functional trajectories associated with acute illness and hospitalization in oldest old patients: Impact on mortality.高龄老人急性疾病和住院相关的功能轨迹:对死亡率的影响。
Front Physiol. 2022 Sep 14;13:937115. doi: 10.3389/fphys.2022.937115. eCollection 2022.
8
Development and validation of predictive model for long-term hospitalization, readmission, and in-hospital death of patients over 60 years old.建立并验证 60 岁以上患者长期住院、再入院和院内死亡的预测模型。
Einstein (Sao Paulo). 2022 Jun 17;20:eAO8012. doi: 10.31744/einstein_journal/2022AO8012. eCollection 2022.
9
Prognostic impact of hospital-acquired disability in elderly patients with heart failure.医院获得性残疾对老年心力衰竭患者的预后影响
ESC Heart Fail. 2021 Jun;8(3):1767-1774. doi: 10.1002/ehf2.13356. Epub 2021 Apr 10.
10
Daytime-to-Nighttime Sleep Ratios and Cognitive Impairment in Older Intensive Care Unit Survivors.日间到夜间睡眠时间比值与老年重症监护病房幸存者的认知障碍。
Am J Crit Care. 2021 Mar 1;30(2):e40-e47. doi: 10.4037/ajcc2021221.