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老年住院患者报告的身体不稳预示着功能衰退。

Unsteadiness reported by older hospitalized patients predicts functional decline.

作者信息

Lindenberger Elizabeth C, Landefeld C Seth, Sands Laura P, Counsell Steven R, Fortinsky Richard H, Palmer Robert M, Kresevic Denise M, Covinsky Kenneth E

机构信息

Division of Geriatrics, San Francisco VA Medical Center, California 94121, USA.

出版信息

J Am Geriatr Soc. 2003 May;51(5):621-6. doi: 10.1034/j.1600-0579.2003.00205.x.

Abstract

OBJECTIVES

To determine whether a simple question about steadiness at admission predicts in-hospital functional decline and whether unsteadiness at admission predicts failure of in-hospital functional recovery of patients who have declined immediately before hospitalization.

DESIGN

Prospective cohort study.

SETTING

One university hospital and one community teaching hospital.

PARTICIPANTS

One thousand five hundred fifty-seven hospitalized medical patients aged 70 and older.

MEASUREMENTS

On admission, patients reported their steadiness with walking and whether they could perform independently each of five basic activities of daily living (ADLs) at admission and 2 weeks before admission (baseline). For the primary analysis, the outcome was decline in ADL function between admission and discharge. For the secondary analysis, the outcome was in-hospital recovery to baseline ADL function in patients who experienced ADL decline in the 2 weeks before admission.

RESULTS

In the primary cohort (n = 1,557), 25% of patients were very unsteady at admission; 22% of very unsteady patients declined during hospitalization, compared with 17%, 18%, and 10% for slightly unsteady, slightly steady, and very steady patients, respectively (P for trend =.001). After adjusting for age; medical comorbidities; Acute Physiology, Age, and Chronic Health Evaluation II score; and admission ADL, unsteadiness remained significantly associated with ADL decline (odds for decline for very unsteady compared with very steady = 2.6, 95% confidence interval = 1.5-4.5). In the secondary analysis, predicting ADL recovery in patients who declined before hospitalization (n = 563), 46% of patients were very unsteady at admission. In this cohort, 44% of very unsteady patients failed to recover, compared with 35%, 36%, and 33% for each successively higher level of steadiness, respectively (P for trend = 0.06). After multivariate adjustment, greater unsteadiness independently predicted failure of recovery (P for trend = 0.02).

CONCLUSION

A simple question about steadiness identified patients at increased risk for in-hospital ADL decline and, in patients who lost ADL function immediately before admission, failure to recover.

摘要

目的

确定入院时一个关于身体稳定性的简单问题能否预测住院期间的功能衰退,以及入院时身体不稳定能否预测住院前功能立即衰退的患者住院期间功能恢复失败。

设计

前瞻性队列研究。

地点

一家大学医院和一家社区教学医院。

参与者

1557名70岁及以上的住院内科患者。

测量

入院时,患者报告其行走稳定性以及入院时和入院前2周(基线)能否独立完成五项基本日常生活活动(ADL)中的每一项。对于主要分析,结局是入院和出院之间ADL功能的衰退。对于次要分析,结局是入院前2周经历ADL衰退的患者住院期间恢复到基线ADL功能。

结果

在主要队列(n = 1557)中,25%的患者入院时非常不稳定;22%非常不稳定的患者在住院期间出现衰退,而轻度不稳定、轻度稳定和非常稳定的患者分别为17%、18%和10%(趋势P值 = 0.001)。在调整年龄、合并症、急性生理学与慢性健康状况评分系统II评分和入院时ADL后,不稳定仍与ADL衰退显著相关(非常不稳定与非常稳定相比衰退的比值 = 2.6,95%置信区间 = 1.5 - 4.5)。在次要分析中,预测住院前衰退患者(n = 563)的ADL恢复情况,46%的患者入院时非常不稳定。在该队列中,44%非常不稳定的患者未能恢复,而稳定性依次更高的患者分别为35%、36%和33%(趋势P值 = 0.06)。多变量调整后,更大程度的不稳定独立预测恢复失败(趋势P值 = 0.02)。

结论

一个关于稳定性的简单问题可识别出住院期间ADL衰退风险增加的患者,以及入院前立即丧失ADL功能的患者恢复失败的风险。

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