Roth D B, Siatkowski R M
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Florida, USA.
Am J Ophthalmol. 2000 Feb;129(2):256-8. doi: 10.1016/s0002-9394(99)00308-6.
To report a patient with large-cell lymphoma of the sphenoid sinus presenting with bilateral blindness and no other signs or symptoms.
Case report. A previously healthy 5-year-old boy complained of sudden vision loss without other systemic complaints.
Ophthalmologic examination revealed no light perception bilaterally. The pupils of the patient were fixed at 8 mm without reaction to the brightest light stimulus. Systemic examination was unremarkable, and neuroimaging revealed a large sphenoid tumor extending intracranially. Biopsy of the tumor proved to be large-cell lymphoma.
Large-cell lymphoma affecting children may present initially with blindness, without other systemic symptoms.
报告一例蝶窦大细胞淋巴瘤患者，该患者表现为双侧失明且无其他体征或症状。
病例报告。一名此前健康的5岁男孩主诉突然视力丧失，无其他全身不适症状。
眼科检查显示双侧无光感。患者瞳孔固定在8毫米，对最强光刺激无反应。全身检查无异常，神经影像学检查显示一个巨大的蝶窦肿瘤向颅内延伸。肿瘤活检证实为大细胞淋巴瘤。
影响儿童的大细胞淋巴瘤最初可能仅表现为失明，而无其他全身症状。
