Ye Huiping, Gong Zhengpeng, Yang Wen, Dai Yubing
Department of Otolaryngology, Head and Neck Surgery, The Affiliated Baiyun Hospital of Guizhou Medical University, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou 550004, P.R. China; Department of Pathology, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou 550004, P.R. China.
Department of Otolaryngology, Head and Neck Surgery, The Affiliated Baiyun Hospital of Guizhou Medical University, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou 550004, P.R. China.
Oncol Lett. 2016 Jun;11(6):4252-4254. doi: 10.3892/ol.2016.4534. Epub 2016 May 6.
Primary non-Hodgkin lymphoma (PNHL) of the sphenoid sinus is a rare neoplasm that poses a diagnostic challenge to clinicians. The proximity of the optical nerve and canal to the sphenoid sinus is accountable for the high incidence of visual disturbance in PNHL of the sphenoid sinus. In particular, patients whose radiologic diagnosis reveals bone destruction in the lateral wall involved with optical-nerve-canals or cavernous sinus present a high risk of rapidly developing unilateral blindness. The present study reports 2 rare cases of PNHL of the sphenoid sinus. Sudden sight loss may follow minimally invasive biopsy. In such cases, the measures that must be taken for the prevention of permanent sight loss are limited in the absence of the final pathologic diagnosis.
蝶窦原发性非霍奇金淋巴瘤（PNHL）是一种罕见肿瘤，给临床医生带来诊断挑战。视神经和神经管与蝶窦位置相邻，这是蝶窦PNHL中视觉障碍高发的原因。特别是，放射学诊断显示外侧壁骨质破坏累及视神经管或海绵窦的患者，有迅速发展为单侧失明的高风险。本研究报告了2例罕见的蝶窦PNHL病例。微创活检后可能会突然失明。在这种情况下，由于缺乏最终病理诊断，预防永久性失明所需采取的措施有限。
