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[超氧化物歧化酶的抗炎作用]

[The anti-inflammatory effects of superoxide dismutase].

作者信息

Xiong Y, Ye S, Liang Y, Song P, Zhou S

机构信息

Department of Pharmacology, School of Basic Medical Sciences, Chengdu.

出版信息

Hua Xi Yi Ke Da Xue Xue Bao. 1997 Mar;28(1):58-61.

Abstract

This paper reports the anti-inflammatory effects of superoxide dismutase (SOD) from pig blood on inflammatory animal models. The experimental results have shown that SOD has significant anti-inflammatory effects. It inhibited carrageenin-induced foot-edema and croton oil induced granulation tissue edema of rats. It also inhibited arthritis induced by egg serum and Freund's adjuvant in rats. The effects were significantly dose-dependent.

摘要

本文报道了猪血超氧化物歧化酶(SOD)对炎症动物模型的抗炎作用。实验结果表明,SOD具有显著的抗炎作用。它抑制了角叉菜胶诱导的大鼠足肿胀和巴豆油诱导的大鼠肉芽组织水肿。它还抑制了大鼠蛋清和弗氏佐剂诱导的关节炎。这些作用具有显著的剂量依赖性。

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