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绒毛蛛猴(Lagothrix lagotricha)的纤维性肾小球肾炎和肺出血

Fibrillary glomerulonephritis and pulmonary haemorrhage in a Woolly monkey (Lagothrix lagotricha).

作者信息

Brown P J, MacIver A G, Harrison R F, Day M J, Skuse A M, Munnings N P

机构信息

Comparative Pathology Laboratory, University of Bristol Veterinary School, Langford, North Somerset, BS40 5DU, UK.

出版信息

J Comp Pathol. 2000 Feb-Apr;122(2-3):209-12. doi: 10.1053/jcpa.1999.0350.

Abstract

Fibrillar deposits, distinct from amyloid deposits, were demonstrated by electron microscopy in the glomeruli and lung of an Amazonian Woolly monkey (Lagothrix lagotricha) which had died with extensive pulmonary haemorrhage. The renal lesions were typical of fibrillary glomerulonephritis in man, and IgG deposition was also demonstrated in the kidney. The association of renal and pulmonary lesions has been reported previously in man, but this is the first report of fibrillary glomerulonephritis, and a pulmonary-renal syndrome, in non-human animals.

摘要

在一只死于广泛肺出血的亚马逊绒毛猴(Lagothrix lagotricha)的肾小球和肺中,通过电子显微镜观察到了与淀粉样沉积物不同的纤维状沉积物。肾脏病变是人类纤维性肾小球肾炎的典型表现,并且在肾脏中也证实有IgG沉积。肾脏和肺部病变的关联此前在人类中有报道,但这是关于非人类动物中纤维性肾小球肾炎和肺肾综合征的首次报告。

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