Njinimbam C G, Hebra A, Kicklighter S D, Bernstein A L, Katikaneni L P, Mulvihill D M, Purohit D M
Department of Pediatrics, Children's Hospital, Medical University of South Carolina, Charleston 29425-3313, USA.
J Perinatol. 1999 Jan;19(1):64-7. doi: 10.1038/sj.jp.7200046.
A full-term neonate is reported with congenital cystic adenomatoid malformation of the lung treated by lobectomy with development of pulmonary hypertension. The infant was successfully treated with extracorporeal membrane oxygenation (ECMO) for persistent pulmonary hypertension, which developed postoperatively. An 18-day course of venovenous ECMO was necessary to effectively reverse the severe pulmonary hypertension. This was probably a result of significant pulmonary hypoplasia of the compressed lung. Although not all congenital cystic adenomatoid malformations of the lung are associated with pulmonary hypoplasia and persistent pulmonary hypertension, this is one case where severe pulmonary hypertension developed secondary to a mass effect by a large lesion in the chest.
据报道，一名足月新生儿患有先天性肺囊性腺瘤样畸形，接受了肺叶切除术，术后出现肺动脉高压。该婴儿因持续性肺动脉高压接受体外膜肺氧合（ECMO）治疗并获得成功，这种肺动脉高压是术后出现的。为有效逆转严重的肺动脉高压，需要进行为期18天的静脉-静脉ECMO治疗。这可能是由于受压肺组织严重肺发育不全所致。虽然并非所有先天性肺囊性腺瘤样畸形都与肺发育不全和持续性肺动脉高压相关，但这是一例因胸部大病变的占位效应继发严重肺动脉高压的病例。
