Wallgren A, Zajicek J
Acta Cytol. 1976 Sep-Oct;20(5):479-85.
The prognostic significance of various morphologic factors (size of nuclei, nucleoli, mitotic frequency, naked carcinoma nuclei, nuclear:cytoplasmic ratio, size of cell clusters, necrotic matter, mucoid matter, and lymphocytes) was studied in aspiration biopsy smears from 494 carcinomas of the breast. A multivariate analysis of clinical and cytologic variables was performed with regard to five-and ten-year survival.
在494例乳腺癌的针吸活检涂片上，研究了各种形态学因素（细胞核大小、核仁、有丝分裂频率、裸癌细胞核、核质比、细胞团大小、坏死物质、黏液物质和淋巴细胞）的预后意义。针对5年和10年生存率，对临床和细胞学变量进行了多变量分析。
