乳腺癌细胞核平均直径的预后意义
Prognostic implications of mean nuclear diameter in breast cancer.
作者信息
van Bogaert L J, de Muylder C, Maldague P, Maisin H
出版信息
Br J Cancer. 1980 Oct;42(4):537-41. doi: 10.1038/bjc.1980.277.
Abstract
The mean nuclear diameter of 100 breast cancers was measured on tissue sections, to evaluate its importance for early prognosis. The cases were subdivided into 3 subgroups: small (25.5% of cases), medium (63.3%) and large (11.2%) nuclei. Early recurrence and mortality rates were investigated in each of the categories. Increasing nuclear size was shown to be related to mortality from metastatic disease. However, large-nucleus tumours had an inverse relationship with lymphnode involvement and possibly with recurrence rate. Hence, in our material nuclear size as a sole criterion was not a good indicator of the early behaviour of operable breast cancer.
摘要
在组织切片上测量了100例乳腺癌的平均核直径，以评估其对早期预后的重要性。这些病例被分为3个亚组：小核（占病例的25.5%）、中核（63.3%）和大核（11.2%）。对每个类别中的早期复发率和死亡率进行了调查。结果显示，核大小增加与转移性疾病导致的死亡率相关。然而，大核肿瘤与淋巴结受累呈负相关，可能也与复发率呈负相关。因此，在我们的研究材料中，仅将核大小作为标准并不是可手术乳腺癌早期行为的良好指标。
相似文献
1
Prognostic implications of mean nuclear diameter in breast cancer.乳腺癌细胞核平均直径的预后意义
Br J Cancer. 1980 Oct;42(4):537-41. doi: 10.1038/bjc.1980.277.
2
Histological grading of breast cancer; significance of grade on recurrence and mortality.乳腺癌的组织学分级；分级对复发和死亡率的意义。
Eur J Surg Oncol. 1989 Feb;15(1):25-31.
3
Nuclear morphometry and mitotic indexes as prognostic factors in breast cancer.细胞核形态测量及有丝分裂指数作为乳腺癌的预后因素
Eur J Surg. 1991 May;157(5):319-24.
4
The relation of prognosis to the nuclear diameter of breast cancer cells obtained by cytologic aspiration.通过细胞学穿刺获取的乳腺癌细胞核直径与预后的关系。
Acta Cytol. 1979 Jan-Feb;23(1):75-80.
5
Breast cancer in young women: clinical, histological and morphometric prognostic factors.年轻女性乳腺癌：临床、组织学及形态学预后因素
Anticancer Res. 1992 Jul-Aug;12(4):1237-42.
6
Soluble and nuclear oestrogen receptor status in human breast cancer in relation to prognosis.人类乳腺癌中可溶性和核雌激素受体状态与预后的关系
Br J Cancer. 1981 Jan;43(1):67-71. doi: 10.1038/bjc.1981.9.
7
Grading and prognosis of invasive ductal mammary carcinoma by nuclear image analysis in tissue sections.通过组织切片的核图像分析对浸润性导管乳腺癌进行分级和预后评估。
Pathol Res Pract. 1989 Nov;185(5):689-93. doi: 10.1016/S0344-0338(89)80218-3.
8
Node-negative breast cancer treated by modified radical mastectomy without adjuvant therapies: variables associated with disease recurrence and survivorship.未接受辅助治疗的改良根治术治疗的淋巴结阴性乳腺癌：与疾病复发和生存相关的变量
J Clin Oncol. 1988 Jan;6(1):83-8. doi: 10.1200/JCO.1988.6.1.83.
9
Response rate to neoadjuvant chemotherapy measured on imaging predicts early recurrence and death in breast cancer patients with lymph node involvements.影像学测量的新辅助化疗反应率可预测有淋巴结受累的乳腺癌患者的早期复发和死亡情况。
Acta Radiol. 2011 Apr 1;52(3):241-6. doi: 10.1258/ar.2010.100334. Epub 2011 Mar 3.
10
A proposal for a new histological classification scheme for predicting short-term tumor recurrence and death in patients with invasive ductal carcinoma of the breast.一项关于预测乳腺浸润性导管癌患者短期肿瘤复发和死亡的新组织学分类方案的提议。
Jpn J Cancer Res. 1998 Dec;89(12):1358-73. doi: 10.1111/j.1349-7006.1998.tb00534.x.
引用本文的文献
1
Organ-specific enhancement of metastasis by spontaneous ploidy duplication and cell size enlargement.自发性倍性复制和细胞体积增大导致器官特异性转移增强。
Cell Res. 2010 Sep;20(9):1012-22. doi: 10.1038/cr.2010.93. Epub 2010 Jul 13.
2
Mean nuclear area and histological grade of axillary-node tumour in breast cancer, related to prognosis.乳腺癌腋窝淋巴结肿瘤的平均核面积和组织学分级与预后的关系。
Br J Cancer. 1982 Jul;46(1):95-100. doi: 10.1038/bjc.1982.170.
本文引用的文献
1
Nuclear diameters of breast cancer cells in tissue sections.组织切片中乳腺癌细胞的核直径。
Anal Quant Cytol. 1980 Mar-Apr;2(1):55-8.
2
[Relationship between sex chromatin incidence, nuclear size and DNA content in breast tumors and its significance for the survuval rate].[乳腺肿瘤中性染色质发生率、核大小与DNA含量之间的关系及其对生存率的意义]
Schweiz Med Wochenschr. 1967 May 27;97(21):678-82.
3
The evaluation of sex chromatin as a prognostic factor in carcinoma of the breast. A preliminary report.性染色质作为乳腺癌预后因素的评估。初步报告。
Acta Cytol. 1971 Jul-Aug;15(4):372-4.
4
The prognostic value of the aspiration biopsy smear in mammary carcinoma.针吸活检涂片在乳腺癌中的预后价值。
Acta Cytol. 1976 Sep-Oct;20(5):479-85.
5
Identification of breast cancer patients with high risk of early recurrence after radical mastectomy. II. Clinical and pathological correlations. A report of the Primary Therapy of Breast Cancer Study Group.根治性乳房切除术后早期复发高危乳腺癌患者的识别。II. 临床与病理相关性。乳腺癌原发性治疗研究组报告
Cancer. 1978 Dec;42(6):2809-26. doi: 10.1002/1097-0142(197812)42:6<2809::aid-cncr2820420642>3.0.co;2-9.
6
Analysis of reproducibility of subjective grading systems for breast carcinoma.乳腺癌主观分级系统的可重复性分析
J Clin Pathol. 1979 Oct;32(10):979-85. doi: 10.1136/jcp.32.10.979.
7
Prognostic value of estrogen receptors in primary breast cancer.雌激素受体在原发性乳腺癌中的预后价值
Cancer. 1979 Aug;44(2):671-5. doi: 10.1002/1097-0142(197908)44:2<671::aid-cncr2820440238>3.0.co;2-v.
8
Relationship between proliferative activity and estrogen receptors in breast cancer.乳腺癌中增殖活性与雌激素受体之间的关系。
Cancer. 1979 Aug;44(2):665-70. doi: 10.1002/1097-0142(197908)44:2<665::aid-cncr2820440237>3.0.co;2-n.
9
Histological grade and other prognostic factors in relation to survival of patients with breast cancer.乳腺癌患者的组织学分级及其他与生存相关的预后因素。
Br J Cancer. 1979 Jul;40(1):44-55. doi: 10.1038/bjc.1979.139.
10
Correlation of estrogen receptor levels with histology and cytomorphology in human mammary cancer.人乳腺癌中雌激素受体水平与组织学及细胞形态学的相关性
Am J Clin Pathol. 1979 May;71(5):497-503. doi: 10.1093/ajcp/71.5.497.
Zotero 插件