Balmysheva N P, Solovenchuk L L
Institute of Biological Problems of the North, Russian Academy of Sciences, Magadan, Russia.
Genetika. 1999 Dec;35(12):1681-6.
RFLP analysis of amplified genes for cytochrome b and NADP dehydrogenase 5/6 of sable mtDNA was carried out. Polymorphism was recorded in the first and the second fragment using six and four enzymes, respectively. This allowed us to identify seven mtDNA haplotypes forming two clusters, A1-A3 and B1-C2. The divergence between the clusters was 0.0112-0.0164. An association between mutations of genes for cytochrome b and NADP dehydrogenase 5/6 was established. This association can be explained by high mutability of the fragments containing the associated mutations.
对紫貂线粒体DNA细胞色素b和NADP脱氢酶5/6的扩增基因进行了限制性片段长度多态性(RFLP)分析。分别使用六种和四种酶在第一个和第二个片段中记录到多态性。这使我们能够识别出形成两个簇(A1 - A3和B1 - C2)的七种线粒体DNA单倍型。簇间的分歧为0.0112 - 0.0164。细胞色素b和NADP脱氢酶5/6基因的突变之间建立了关联。这种关联可以通过含有相关突变的片段的高突变性来解释。