[手足多指（趾）畸形]

[Polydactyly of the hand and foot].

作者信息

Minguella-Solá J, Cabrera-González M

机构信息

Unidad de Malformaciones de las Extremidades, Centro Médico Teknon, Barcelona.

出版信息

An Esp Pediatr. 1999 Oct;51(4):357-60.

PMID:10690227

Abstract

OBJECTIVE

Our aim was to establish the differences between polydactyly of the hand, the foot and those affecting both the hands and feet.

PATIENTS AND METHODS

One hundred twenty-five cases of hand polydactyly (HP), 105 of foot polydactyly (FP) and 25 cases of combined hand and foot polydactyly (HFP) were reviewed. We differentiated between preaxial, postaxial, axial and peculiar polydactyly and a group constituted by all other non-preaxial location (OTHERL) was also formed. In all patients the following parameters were analyzed: sex, laterality, antecedence of malformation in the family (FAANT) and the existence of other malformations (OTHERM).

RESULTS

Polydactyly was commonly preaxial in the hand (72%), OTHERL in the foot (64.7%) and equally located in hands and feet in HFP, with the most frequent being postaxial/postaxial combination (36% of the cases). Bilaterality is rare in preaxial HP (3.3% versus 77.7% of right unilaterality) and remarkable in OTHERL (54.2%). Bilaterality is greater in preaxial FP (64.8%) and strongly marked in HFP, which accounts for 72% of hands and 80% of feet. There is a slight global dominance of males in all forms. The existence of FAANT is higher in OTHERL in the hand (45.7% versus 34.4% in preaxial) and in preaxial of the foot (45.9% versus 25% in OTHERL), being very high (48%) in HFP. The coexistence with other malformations, either in the hand or foot, is higher in OTHERL.

摘要

目的

我们的目的是确定手部多指、足部多指以及同时影响手部和足部的多指之间的差异。

患者与方法

回顾了125例手部多指（HP）、105例足部多指（FP）和25例手足联合多指（HFP）病例。我们区分了轴前型、轴后型、中央型和特殊型多指，并形成了一个由所有其他非轴前位置组成的组（OTHERL）。对所有患者分析了以下参数：性别、侧别、家族中畸形的先行情况（FAANT）以及其他畸形的存在情况（OTHERM）。

结果

多指在手部通常为轴前型（72%），在足部为OTHERL型（64.7%），在HFP中手部和足部的分布相同，最常见的是轴后/轴后组合（占病例的36%）。轴前型HP双侧受累罕见（3.3%，而右侧单侧受累为77.7%），在OTHERL中则较为显著（54.2%）。轴前型FP双侧受累比例更高（64.8%），在HFP中更为明显，手部占72%，足部占80%。在所有类型中男性总体上略占优势。手部OTHERL中FAANT的存在率更高（45.7%，而轴前型为34.4%），足部轴前型中FAANT的存在率也更高（45.9%，而OTHERL中为25%），在HFP中非常高（48%）。手部或足部与其他畸形共存的情况在OTHERL中更高。