Miura T, Nakamura R, Imamura T
J Hand Surg Am. 1987 May;12(3):474-6. doi: 10.1016/s0363-5023(87)80027-8.
Polydactyly of the hand, of the foot, and of the hand combined with the foot were studied. As noted in previous reports of polydactyly, inherited cases represent about 10% of polydactyly of the hand or foot, and unilateral involvement is more common than bilateral. In 495 cases of polydactyly 27 patients had polydactyly of the hands and feet. The extra digits in 21 of those 27 were in the same digital rays of the hand and foot. There were 14 inherited cases (51.9%) and most were an autosomal dominant, but some were an autosomal recessive. Both hand and/or feet were involved in 22 cases. Most cases of preaxial polydactyly of the hand combined with central polydactyly of the foot were sporadic and unilateral. All cases of both preaxial and postaxial (polyaxial) polydactyly were inherited and bilateral. Two pairs of sisters had the same clinical features. The parent (mother or father) also had the same deformities in the inherited cases.
对多指畸形累及手部、足部以及同时累及手部和足部的情况进行了研究。正如之前关于多指畸形的报告中所指出的，遗传性病例约占手部或足部多指畸形的10%，单侧受累比双侧受累更为常见。在495例多指畸形病例中，有27例患者手部和足部均有多指畸形。这27例患者中有21例的多余手指位于手部和足部的同一手指射线。有14例遗传性病例（51.9%），大多数为常染色体显性遗传，但也有一些是常染色体隐性遗传。22例患者的手部和/或足部均受累。手部轴前多指畸形合并足部中央多指畸形的大多数病例为散发且单侧。所有轴前和轴后（多轴）多指畸形病例均为遗传性且双侧受累。有两对姐妹具有相同的临床特征。在遗传性病例中，父母（母亲或父亲）也有相同的畸形。
