Macleod U, Ross S, Gillis C, McConnachie A, Twelves C, Watt G C
Department of General Practice, University of Glasgow, UK.
Ann Oncol. 2000 Jan;11(1):105-7. doi: 10.1023/a:1008385321476.
This study describes and compares the pathological prognostic factors and surgeon assessment of stage of breast cancer of women living in affluent and deprived areas to assess whether clinical stage at presentation may explain the known poorer survival outcomes for deprived women.
A population-based review of the case records of 417 women with breast cancer was carried out.
No difference in pathological criteria was found between the 88% of women living in affluent and deprived areas for whom such data were available. Clinical assessment of the remaining 50 cases showed that women living in deprived areas were more likely to present with locally advanced or metastatic disease.
The poorer survival of women from deprived areas with breast cancer may be explained by more deprived women presenting with advanced cancers.
本研究描述并比较了生活在富裕地区和贫困地区的女性乳腺癌患者的病理预后因素及外科医生对疾病分期的评估,以确定就诊时的临床分期是否可以解释贫困女性已知的较差生存结果。
对417例乳腺癌女性患者的病例记录进行了基于人群的回顾。
在有此类数据的88%的生活在富裕地区和贫困地区的女性中,未发现病理标准存在差异。对其余50例患者的临床评估显示,生活在贫困地区的女性更有可能出现局部晚期或转移性疾病。
贫困地区乳腺癌女性患者较差的生存率可能是由于更多贫困女性患有晚期癌症。