Jauk B, Mikosch P, Gallowitsch H J, Kresnik E, Molnar M, Gomez I, Lind P
Department of Nuclear Medicine and Special Endocrinology, LKH Klagenfurt, Austria.
Thyroid. 2000 Jan;10(1):93-5. doi: 10.1089/thy.2000.10.93.
We report a 50-year-old woman, with overt hypothyroidism undergoing thyrotropin (TSH)-stimulating hormone suppressive levothyroxine (LT4) treatment after subtotal thyroidectomy. At her first visit to our department, the laboratory results revealed a borderline low free thyroxine (FT4) level accompanied by a clearly elevated TSH level. Both parameters did not significantly change during therapy with an oral dose of 500 microg of LT4. Investigations revealed malabsorption of oral administrated LT4. Thyroid serum hormone levels only became normal during parenteral therapy with LT4.
我们报告了一名50岁女性，她患有明显的甲状腺功能减退症，在甲状腺次全切除术后接受促甲状腺素（TSH）刺激激素抑制性左甲状腺素（LT4）治疗。在她首次到我们科室就诊时，实验室检查结果显示游离甲状腺素（FT4）水平略低，同时促甲状腺激素（TSH）水平明显升高。口服500微克LT4治疗期间，这两个参数均无明显变化。检查发现口服LT4存在吸收不良。仅在接受LT4肠外治疗期间，甲状腺血清激素水平才恢复正常。
