Akmaz O, Erel A, Gürer M A
Dermatology Department, Faculty of Medicine, Gazi University, Ankara, Turkey.
Int J Dermatol. 2000 Feb;39(2):121-5. doi: 10.1046/j.1365-4362.2000.00884.x.
The pathergy test, an important test in the diagnosis of Behçet's disease, is currently applied with disposable/sharp needles and evaluated only clinically (no histopathologic evaluation). In this study, the usefulness of the pathergy test conducted intradermally and intravenously with disposable/sharp needles in the diagnosis and determination of the activation of the disease is studied in comparison with the test conducted with nondisposable/blunt needles. In addition, histopathologic evaluation of the pathergy test is compared with the clinical evaluation.
The study group consists of 43 Behçet's disease patients together with 15 patients with dermatosis as the control group. The pathergy test was applied to the Behçet's disease patients and the control group intradermally and intravenously with disposable/sharp and nondisposable/blunt needles.
The results of the pathergy test on the patients and the control group were evaluated clinically and histopathologically.
Clinical evaluation of the pathergy test conducted intradermally with nondisposable/blunt needles is sufficient for both the diagnosis and determination of the activation of Behçet's disease. Histopathologic evaluation of the test is not found to be more sensitive than the clinical evaluation.
针刺反应试验是白塞病诊断中的一项重要试验，目前使用一次性/尖锐针头进行，且仅通过临床评估（无组织病理学评估）。在本研究中，将使用一次性/尖锐针头进行的皮内和静脉针刺反应试验与使用非一次性/钝针头进行的试验相比较，研究其在白塞病诊断和疾病活动度判定中的效用。此外，将针刺反应试验的组织病理学评估与临床评估进行比较。
研究组由43例白塞病患者和15例皮肤病患者作为对照组组成。对研究组白塞病患者和对照组进行皮内和静脉针刺反应试验，分别使用一次性/尖锐针头和非一次性/钝针头。
对患者和对照组针刺反应试验的结果进行了临床和组织病理学评估。
使用非一次性/钝针头进行皮内针刺反应试验的临床评估对白塞病的诊断和疾病活动度判定均足够。未发现该试验的组织病理学评估比临床评估更敏感。
