Tan E K
Department of Neurology, Singapore General Hospital, Singapore.
Int J Clin Pract. 1999 Dec;53(8):623-6.
The recent resurgence of surgical treatment of Parkinson's disease has generated enormous interest in the scientific community and with the general public. Both ablation (pallidotomy, thalamotomy), deep brain stimulation (thalamus, pallidum, subthalamus), and neural transplantation (human, porcine) have been demonstrated to be effective for specific subsets of Parkinson's disease patients. Future studies need to define better the ideal target sites and lesion volume of ablation and stimulation procedures, and optimising graft survival in neural transplantation. Numerous potential surgical interventions are currently being evaluated.
帕金森病外科治疗最近的复兴引起了科学界和普通大众的极大兴趣。毁损术（苍白球切开术、丘脑切开术）、深部脑刺激（丘脑、苍白球、下丘脑）以及神经移植（人源、猪源）已被证明对特定亚组的帕金森病患者有效。未来的研究需要更好地确定毁损和刺激手术的理想靶点及损伤体积，并优化神经移植中的移植物存活情况。目前正在评估众多潜在的外科干预措施。
