结核分枝杆菌中异烟肼耐药性的分子基础。 - Suppr

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超能文献

The molecular basis of isoniazid resistance in Mycobacterium tuberculosis.

作者信息

Heym B, Saint-Joanis B, Cole S T

机构信息

Service de Microbiologie, Hôpital Ambroise-Paré, Boulogne, France.

出版信息

Tuber Lung Dis. 1999;79(4):267-71. doi: 10.1054/tuld.1998.0208.

DOI:10.1054/tuld.1998.0208

PMID:10692996

Abstract

摘要

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The molecular basis of isoniazid resistance in Mycobacterium tuberculosis.结核分枝杆菌中异烟肼耐药性的分子基础。

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Transformation with katG restores isoniazid-sensitivity in Mycobacterium tuberculosis isolates resistant to a range of drug concentrations.用katG进行转化可恢复对一系列药物浓度耐药的结核分枝杆菌分离株的异烟肼敏感性。

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