PTEN在肿瘤抑制中的多重作用。 - Suppr

The multiple roles of PTEN in tumor suppression.

作者信息

Di Cristofano A, Pandolfi P P

机构信息

Department of Human Genetics, Memorial Sloan-Kettering Cancer Center, Sloan-Kettering Institute, New York, New York 10021, USA.

出版信息

Cell. 2000 Feb 18;100(4):387-90. doi: 10.1016/s0092-8674(00)80674-1.

DOI:10.1016/s0092-8674(00)80674-1

PMID:10693755

Abstract

摘要

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The multiple roles of PTEN in tumor suppression.

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引用本文的文献

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The multiple roles of PTEN in tumor suppression.

作者信息

Di Cristofano A, Pandolfi P P

机构信息

Department of Human Genetics, Memorial Sloan-Kettering Cancer Center, Sloan-Kettering Institute, New York, New York 10021, USA.

出版信息

Cell. 2000 Feb 18;100(4):387-90. doi: 10.1016/s0092-8674(00)80674-1.

DOI:10.1016/s0092-8674(00)80674-1

PMID:10693755

Abstract

摘要

相似文献

The multiple roles of PTEN in tumor suppression.

Cell. 2000 Feb 18;100(4):387-90. doi: 10.1016/s0092-8674(00)80674-1.

The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling.

Biochim Biophys Acta. 2000 Feb 14;1470(1):M21-35. doi: 10.1016/s0304-419x(99)00032-3.

Stem cells. PTEN--coupling tumor suppression to stem cells?

Science. 2001 Dec 7;294(5549):2116-8. doi: 10.1126/science.1067931.

Gatekeeper for endometrium: the PTEN tumor suppressor gene.

J Natl Cancer Inst. 2000 Jun 7;92(11):861-3. doi: 10.1093/jnci/92.11.861.

Pten, a protean tumor suppressor.

Am J Pathol. 2001 Jun;158(6):1895-8. doi: 10.1016/S0002-9440(10)64656-1.

PTEN: life as a tumor suppressor.

Exp Cell Res. 2001 Mar 10;264(1):29-41. doi: 10.1006/excr.2000.5130.

[Genes & cancer. Card no. 28: PTEN (MMAC, TEP-1) (phosphatase and tensin homolog deleted on chromosome 10)].

Bull Cancer. 1999 Sep;86(9):715-6.

[PTEN: a tumor suppressor with original properties].

Bull Cancer. 1999 Jun;86(6):522-5.

PTEN.

Curr Biol. 2001 Jul 10;11(13):R502. doi: 10.1016/s0960-9822(01)00303-7.

[PTEN tumor suppressor: functions as a lipid phosphatase].

Tanpakushitsu Kakusan Koso. 2000 Oct;45(14):2405-14.

引用本文的文献

PTEN protein phosphatase activity regulates metastasis by targeting PKCδ.

iScience. 2025 May 26;28(6):112741. doi: 10.1016/j.isci.2025.112741. eCollection 2025 Jun 20.

PTEN neddylation aggravates CDK4/6 inhibitor resistance in breast cancer.

Oncogene. 2025 Jun 18. doi: 10.1038/s41388-025-03468-z.

Examination of PDK1/AKT/mTOR transcription and exosomal mRNA levels in human glioblastoma cell line treated with a combination of temozolomide and hesperidin.

Naunyn Schmiedebergs Arch Pharmacol. 2025 May 15. doi: 10.1007/s00210-025-04137-4.

Prognostic value of FLOT1-related gene signature in head and neck squamous cell carcinoma: insights into radioresistance mechanisms and clinical outcomes.

Cell Death Discov. 2025 May 7;11(1):224. doi: 10.1038/s41420-025-02500-1.

Hepatic ChREBP reciprocally modulates systemic insulin sensitivity in NAFLD.

J Biol Chem. 2025 Apr 29;301(6):108556. doi: 10.1016/j.jbc.2025.108556.

Regulation of Apoptotic Pathways by MicroRNAs: A Therapeutic Strategy for Alzheimer's Disease.

Mol Neurobiol. 2025 Apr 12. doi: 10.1007/s12035-025-04833-5.

DeepMethyGene: a deep-learning model to predict gene expression using DNA methylations.

BMC Bioinformatics. 2025 Apr 8;26(1):99. doi: 10.1186/s12859-025-06115-2.

Key roles of ubiquitination in regulating critical regulators of cancer stem cell functionality.

Genes Dis. 2024 Apr 17;12(3):101311. doi: 10.1016/j.gendis.2024.101311. eCollection 2025 May.

Hyperactivation of the PI3K pathway in inborn errors of immunity: current understanding and therapeutic perspectives.

Immunother Adv. 2024 Nov 7;4(1):ltae009. doi: 10.1093/immadv/ltae009. eCollection 2024.

Circulating mRNA Expression of VEGF, PTEN, and SOCS1 as Potential Prognostic Predictor for Nasopharyngeal Carcinoma Progression.

Asian Pac J Cancer Prev. 2024 Sep 1;25(9):2999-3006. doi: 10.31557/APJCP.2024.25.9.2999.

The multiple roles of PTEN in tumor suppression.

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The multiple roles of PTEN in tumor suppression.

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