Sokka T, Kankainen A, Hannonen P
Department of Medicine, Jyväskylä Central Hospital, Finland.
Arthritis Rheum. 2000 Feb;43(2):386-9. doi: 10.1002/1529-0131(200002)43:2<386::AID-ANR19>3.0.CO;2-Z.
To analyze correlations of functional disability scores with other measures of clinical status, in particular, Larsen radiographic scores and pain scores, in patients with rheumatoid arthritis (RA).
The functional capacity of 141 patients with RA (102 women, 39 men; median age 57 years; median disease duration 11.8 years; 83% rheumatoid factor positive) was assessed according to the Stanford Health Assessment Questionnaire (HAQ). Other variables studied included Larsen scores for radiographic damage of the small joints of the hands, wrists, and feet, pain scores by visual analog scale (VAS), Disease Activity Scores, general health scores by VAS, and Beck Depression Inventory (BDI) scores.
The Spearman correlation coefficient comparing HAQ and Larsen scores was 0.277 (P = 0.001) and between HAQ and pain scores 0.652 (P < 0.001). In regression analysis, pain scores explained 41.4% of the variation in HAQ scores, normalized Larsen scores explained 7.3%, and BDI scores explained 5.5%; other variables were not significant in the model.
Functional capacity scores of patients with RA are correlated at higher levels with pain scores than with radiographic scores of small joints.
分析类风湿关节炎(RA)患者功能残疾评分与其他临床状态指标,尤其是 Larsen 影像学评分和疼痛评分之间的相关性。
根据斯坦福健康评估问卷(HAQ)对 141 例 RA 患者(102 例女性,39 例男性;中位年龄 57 岁;中位病程 11.8 年;83%类风湿因子阳性)的功能能力进行评估。研究的其他变量包括手部、腕部和足部小关节影像学损伤的 Larsen 评分、视觉模拟量表(VAS)疼痛评分、疾病活动评分、VAS 总体健康评分以及贝克抑郁量表(BDI)评分。
比较 HAQ 和 Larsen 评分的 Spearman 相关系数为 0.277(P = 0.001),HAQ 和疼痛评分之间的相关系数为 0.652(P < 0.001)。在回归分析中,疼痛评分解释了 HAQ 评分变异的 41.4%,标准化 Larsen 评分解释了 7.3%,BDI 评分解释了 5.5%;模型中的其他变量无统计学意义。
RA 患者的功能能力评分与疼痛评分的相关性高于与小关节影像学评分的相关性。