Arikawa J, Higaki Y, Mizushima J, Nogita T, Kawashima M
Department of Dermatology, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666 Japan.
Eur J Dermatol. 2000 Jan-Feb;10(1):52-4.
A 68-year-old woman developed large subcutaneous masses on her abdomen and thighs after a bruise sustained in a traffic accident. She had severe pain when sitting up straight. Histological examination revealed calcified tissues in the entire dermis of the injured areas. On electron microscopy, crystalline materials were observed in the dermis, which seemed to be formed by the deposition of hydroxyapatite on unusual proteoglycan. In a vessel wall, a thick, layered basement membrane was observed. This suggests that vascular injury and subsequent hypoxia play a role in the process of calcinosis. We performed a partial resection with good results in alleviating the patient's pain.
一名68岁女性在交通事故中受伤出现瘀伤后，腹部和大腿出现大量皮下肿块。她直坐时会感到剧痛。组织学检查显示受伤部位整个真皮层有钙化组织。电子显微镜检查发现真皮层有晶体物质，似乎是由羟基磷灰石在异常蛋白聚糖上沉积形成的。在血管壁上，观察到一层厚厚的分层基底膜。这表明血管损伤及随后的缺氧在钙质沉着过程中起作用。我们进行了部分切除，在缓解患者疼痛方面取得了良好效果。
