Gruber O, Northoff G, Pflug B
Psychiatrische Klinik, Universität Frankfurt am Main.
Nervenarzt. 2000 Jan;71(1):30-7. doi: 10.1007/s001150050004.
In this study, we investigated experimentally the effects of different activation procedures on both motor and psychic symptoms in of 11 in-patients with acute neuroleptic-induced akathisia using the Hillside and Barnes akathisia rating scales and videotape rating technique. Motor activation was achieved by finger tapping. Cognitive activation tasks consisted of sequences of mental calculations which were designed either to be easy to perform or to produce stress due to a given time limit or to more difficult calculation operations, respectively. Motor as well as psychic symptoms of akathisia decreased during both motor and simple cognitive activation without stress. By contrast, stress-producing calculation tasks led to an increase in motor and psychic symptoms immediately following the task performance. These possibly specific effects of activation procedures on symptoms might be useful in differentiating acute neuroleptic-induced akathisia from other neuroleptic-induced and extrapyramidal movement disorders.
在本研究中，我们使用希尔赛德（Hillside）和巴恩斯（Barnes）静坐不能评定量表以及录像评定技术，对11例急性抗精神病药物所致静坐不能的住院患者，通过实验研究了不同激活程序对运动和精神症状的影响。通过手指敲击实现运动激活。认知激活任务包括一系列心算，这些心算分别设计为易于执行、因给定时间限制而产生压力或因更困难的计算操作而产生压力。在无压力的运动和简单认知激活过程中，静坐不能的运动和精神症状均有所减轻。相比之下，产生压力的心算任务在任务执行后立即导致运动和精神症状增加。激活程序对症状的这些可能的特定影响，可能有助于区分急性抗精神病药物所致静坐不能与其他抗精神病药物所致及锥体外系运动障碍。
