Lerch C, Park G R
John Farman Intensive Care Unit, Addenbrooke's Hospital, Cambridge, UK.
Br Med Bull. 1999;55(1):76-95. doi: 10.1258/0007142991902303.
Sedation is a process of soothing. The concept of the ideal level of sedation is controversial and has changed over the last decade. A shift from deep sedation, often enhanced by muscle relaxants that completely detaches the patient from their environment, to light sedation rendering the patient sleepy but easily arousable has been widely accepted. This change in attitude has been brought about by sophisticated modes of ventilation allowing the ventilator to synchronize with the patient's own breathing pattern. In addition, the increasingly recognised adverse effects of over-sedation have contributed to the reduction in the depth of sedation.
镇静是一种舒缓的过程。理想镇静水平的概念存在争议,并且在过去十年中发生了变化。从通常由肌肉松弛剂增强的深度镇静(这种深度镇静会使患者完全脱离其周围环境)转向轻度镇静(使患者困倦但易于唤醒)的转变已被广泛接受。这种态度的转变是由先进的通气模式带来的,这些模式使呼吸机能够与患者自身的呼吸模式同步。此外,过度镇静日益被认识到的不良反应也促使了镇静深度的降低。