Przewłocka-Kosmala M, Kosmala W
Katedry i Kliniki Kardiologii, Akademii Medycznej we Wrocławiu.
Przegl Lek. 1999;56(10):671-5.
The high prevalence of restenosis is considered as a main problem concerning transluminal coronary angioplasty--known and popular invasive method of treatment of coronary heart disease. Mechanisms responsible for vascular wall healing and--also--restenosis as well as the role of cells and its mediators are discussed. The prevention of restenosis is a big challenge for contemporary medicine. The investigations concerning methods which theoretically seem to be justified are being conducted. Unfortunately the results of many trials are unconvincing. At present the most important ways of prevention of restenosis are stent implantation and antiplatelet drugs.
再狭窄的高发生率被认为是经皮腔内冠状动脉成形术（一种已知且常用的冠心病侵入性治疗方法）的主要问题。文中讨论了负责血管壁愈合以及再狭窄的机制，以及细胞及其介质的作用。预防再狭窄是当代医学面临的一大挑战。目前正在对理论上似乎合理的方法进行研究。不幸的是，许多试验的结果并不令人信服。目前预防再狭窄最重要的方法是支架植入和抗血小板药物。
