[Restenosis after percutaneous transluminal coronary angioplasty and its prevention].

The high prevalence of restenosis is considered as a main problem concerning transluminal coronary angioplasty--known and popular invasive method of treatment of coronary heart disease. Mechanisms responsible for vascular wall healing and--also--restenosis as well as the role of cells and its mediators are discussed. The prevention of restenosis is a big challenge for contemporary medicine. The investigations concerning methods which theoretically seem to be justified are being conducted. Unfortunately the results of many trials are unconvincing. At present the most important ways of prevention of restenosis are stent implantation and antiplatelet drugs.