Takita H, Minowada J, Han T, Takada M, Lane W W
Ann N Y Acad Sci. 1976;277(00):345-54. doi: 10.1111/j.1749-6632.1976.tb41713.x.
Ten patients with locally far advanced bronchogenic carcinoma were treated with autologous tumor vaccine after a radical surgical resection. Three of 10 patients treated with tumor vaccine are alive (median survival of 26 months) whereas all nine patients in the control group are dead (median survival of 6.5 months). Active immunotherapy adjunct to radical surgery appeared to improve cellular immunity of the treated patients in the postoperative period, and the migration inhibition test indicated sensitization of treated patients against their tumor.
10例局部晚期支气管源性癌患者在根治性手术切除后接受了自体肿瘤疫苗治疗。接受肿瘤疫苗治疗的10例患者中有3例存活（中位生存期26个月），而对照组的9例患者均已死亡（中位生存期6.5个月）。根治性手术辅以主动免疫治疗似乎可改善治疗患者术后的细胞免疫，迁移抑制试验表明治疗患者对其肿瘤产生了致敏作用。
