Pardasani A G, Feldman S R, Clark A R
Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.
Am Fam Physician. 2000 Feb 1;61(3):725-33, 736.
Psoriasis is characterized by red, thickened plaques with a silvery scale. The lesions vary in size and degree of inflammation. Psoriasis is categorized as localized or generalized, based on the severity of the disease and its overall impact on the patient's quality of life and well-being. Patient education about the disease and the treatment options is important. Medical treatment for localized psoriasis begins with a combination of topical corticosteroids and coal tar or calcipotriene. For lesions that are difficult to control with initial therapy, anthralin or tazarotene may be tried. The primary goal of therapy is to maintain control of the lesions. Cure is seldom achieved. If control becomes difficult or if psoriasis is generalized, the patient may benefit from phototherapy, systemic therapy and referral to a physician who specializes in the treatment of psoriasis.
银屑病的特征是出现带有银色鳞屑的红色增厚斑块。皮损在大小和炎症程度上有所不同。根据疾病的严重程度及其对患者生活质量和健康的总体影响，银屑病可分为局限性或全身性。对患者进行有关该疾病及其治疗选择的教育很重要。局限性银屑病的药物治疗首先是外用皮质类固醇与煤焦油或卡泊三醇联合使用。对于初始治疗难以控制的皮损，可尝试使用蒽林或他扎罗汀。治疗的主要目标是维持对皮损的控制。很少能实现治愈。如果控制变得困难或银屑病是全身性的，患者可能会从光疗、全身治疗以及转诊至专门治疗银屑病的医生处获益。
