Sukthana Y
Department of Protozoology Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Southeast Asian J Trop Med Public Health. 1999 Mar;30(1):38-41.
Toxoplasma gondii IgG and IgM antibodies of Thai and Austrian pregnant women were studied, in the same laboratory unit, by using the Sabin-Feldman dye test and ISAGA-IgM. In Thai pregnant women, IgG antibody was found in 21.7%, mostly the IgG titers were low and all were negative for IgM antibody. Conversely in Austrian pregnant women, IgG antibody was found in 30.0% with high titer, and there were 19 (6.3%) cases positive for IgM antibody. The seropositivity of T. gondii IgG antibody in Austrian pregnant women was significantly higher than in Thai (p = 0.02) and the titers were much higher. Two possibilities are postulated to explain the data: it may be because Thai women were infected at a younger age than Austrian women, so they were in the chronic infection stage corresponding with their negativity of IgM antibody or it may be due to the difference of strain virulence of T. gondii from the different parts of the world.
在同一实验室单位，使用Sabin-Feldman染色试验和ISAGA-IgM对泰国和奥地利孕妇的弓形虫IgG和IgM抗体进行了研究。在泰国孕妇中，21.7%检测到IgG抗体，大多数IgG滴度较低，且所有孕妇的IgM抗体均为阴性。相反，在奥地利孕妇中，30.0%检测到高滴度的IgG抗体，有19例（6.3%）IgM抗体呈阳性。奥地利孕妇弓形虫IgG抗体的血清阳性率显著高于泰国孕妇（p = 0.02），且滴度更高。推测有两种可能性来解释这些数据：可能是因为泰国女性比奥地利女性感染年龄更小，所以她们处于与IgM抗体阴性相对应的慢性感染阶段；或者可能是由于来自世界不同地区的弓形虫菌株毒力存在差异。
