南美洲哥伦比亚卡利市孕妇弓形虫感染率
Prevalence of infection with Toxoplasma gondii among pregnant women in Cali, Colombia, South America.
作者信息
Rosso Fernando, Les Jessica T, Agudelo Alejandro, Villalobos Carlos, Chaves José A, Tunubala Gloria Anais, Messa Adriana, Remington Jack S, Montoya José G
机构信息
Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
出版信息
Am J Trop Med Hyg. 2008 Mar;78(3):504-8.
The aim of this study was to determine the prevalence of toxoplasma antibodies among pregnant women in Cali, Colombia. In 2005, 955 pregnant women were tested for IgG and IgM antibodies and sociodemographic information was collected. Their average age was 25.1 years, overall IgG seroprevalence 45.8% (95% CI: 41.8%, 48.2%), IgM 2.8% (95% CI: 1.5%, 3.6%). Seroprevalence increased significantly with age, 39.0% in 14 to 19 years to 55.3% in 30 to 39 years (P = 0.001). There was a significant trend toward a higher seroprevalence in the lower socioeconomic strata (SES) (low: 49.0%, high: 29%, P = 0.004). The increase in seroprevalence by age was more significant in the lower socioeconomic strata (P = 0.002). Our results suggest a higher prevalence when compared with those of the national 1980 (33-37.6%) survey. In contrast to reports from other regions of the world, Cali has not seen a decrease in T. gondii seroprevalence over the past 25 years.
本研究旨在确定哥伦比亚卡利市孕妇弓形虫抗体的流行情况。2005年，对955名孕妇进行了IgG和IgM抗体检测，并收集了社会人口统计学信息。她们的平均年龄为25.1岁，总体IgG血清阳性率为45.8%（95%可信区间：41.8%，48.2%），IgM为2.8%（95%可信区间：1.5%，3.6%）。血清阳性率随年龄显著增加，14至19岁为39.0%，30至39岁为55.3%（P = 0.001）。社会经济地位较低阶层（SES）的血清阳性率有显著升高趋势（低：49.0%，高：29%，P = 0.004）。社会经济地位较低阶层中，血清阳性率随年龄的增加更为显著（P = 0.002）。我们的结果表明，与1980年全国调查（33 - 37.6%）相比，流行率更高。与世界其他地区的报告不同，在过去25年里，卡利市的弓形虫血清阳性率并未下降。
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