Dastidar P, Heinonen T, Ahonen J P, Jehkonen M, Molnár G
Department of Diagnostic Radiology, Tampere University Hospital, Finland.
Comput Biol Med. 2000 Jan;30(1):41-54. doi: 10.1016/s0010-4825(99)00022-0.
The applications of a new segmentation software, Anatomatic, in the evaluation of volumetric measurements of brain infarctions and the new Medimag 3D software in the evaluation of 3D image representation of infarctions are described. These programs are applied to magnetic resonance imaging. The aim of this study is to evaluate the use of these software packages in making accurate volumetric measurements in 40 patients with right cerebral infarctions, in determining the correlations between the quantitated lesions and neurological/neuropsychological dysfunctions and in creating realistic 3D views of the infarctions. Using Anatomatic, reproducible infarction volumes were achieved with ease and within a reasonably fast time. Medimag helped achieve realistic 3D representations of the infarctions. When compared, the semiautomatic segmentation proved to be much faster and yielded higher infarction volumes than the manual segmentation technique. Significantly positive correlations between the infarction volumes and neurological dysfunctions and neuropsychological deficit (neglect) helped to explain the effect of volumes on the clinical status of the patients.
本文描述了一种新型分割软件Anatomatic在脑梗死体积测量评估中的应用，以及新型Medimag 3D软件在梗死灶三维图像呈现评估中的应用。这些程序应用于磁共振成像。本研究的目的是评估这些软件包在对40例右侧脑梗死患者进行准确体积测量、确定定量病变与神经/神经心理功能障碍之间的相关性以及创建梗死灶逼真三维视图方面的用途。使用Anatomatic能够轻松且在合理的短时间内获得可重复的梗死体积。Medimag有助于实现梗死灶逼真的三维呈现。相比之下，半自动分割被证明比手动分割技术快得多，且产生的梗死体积更大。梗死体积与神经功能障碍和神经心理缺陷（忽视）之间显著的正相关有助于解释体积对患者临床状况的影响。
