Seidenwurm D J, McDonnell C H, Raghavan N, Breslau J
Radiological Associates of Sacramento Medical Group, Inc, Sacramento, CA 95814, USA.
AJNR Am J Neuroradiol. 2000 Feb;21(2):426-33.
Our purpose was to evaluate the cost-effectiveness of clinical versus radiographic screening for an orbital foreign body before MR imaging.
Costs of screening were determined on the basis of published reports, disability rating guides, and a practice survey. Base case estimates were derived from published guidelines. A single-state change model was constructed using social cost as the unit of analysis. Sensitivity analysis was performed for each variable. The benefit of screening was avoidance of immediate, permanent, nonameliorable, unilateral blindness.
Using base case estimates and a discount rate of zero, we calculated the cost of the current guideline as $328,580 per quality-adjusted life-year saved. Sensitivity analysis identified screening cost as a critical variable. Discount rates and effectiveness of foreign body removal also were found to be important factors. Probability of injury and prevalence of foreign body may impact the analysis.
Clinical screening before radiography increases the cost-effectiveness of foreign body screening by an order of magnitude, assuming base case ocular foreign body removal rates. Asking the patient "Did a doctor get it all out?" serves this purpose. Occupational history by itself is not sufficient to mandate radiographic orbital screening. Current practice guidelines for foreign body screening should be altered.
我们的目的是评估在进行磁共振成像(MR)之前,临床筛查与影像学筛查眼眶异物的成本效益。
筛查成本是根据已发表的报告、残疾评定指南和一项实践调查确定的。基础病例估计值来自已发表的指南。构建了一个以社会成本为分析单位的单状态变化模型。对每个变量进行了敏感性分析。筛查的益处是避免立即发生的、永久性的、不可改善的单侧失明。
使用基础病例估计值和零贴现率,我们计算出当前指南的成本为每挽救一个质量调整生命年328,580美元。敏感性分析确定筛查成本是一个关键变量。贴现率和异物取出的有效性也被发现是重要因素。受伤概率和异物患病率可能会影响分析。
假设基础病例眼眶异物取出率,在进行影像学检查之前进行临床筛查可将异物筛查的成本效益提高一个数量级。询问患者“医生把它都取出来了吗?”可达到此目的。仅凭职业史不足以强制进行眼眶影像学筛查。当前的异物筛查实践指南应予以修改。