脉络丛以及血液与脑脊液之间的屏障。
The choroid plexuses and the barriers between the blood and the cerebrospinal fluid.
作者信息
Segal M B
机构信息
Division of Physiology, Guy's, King's and St. Thomas' School of Biomedical Sciences, King's College London, UK.
出版信息
Cell Mol Neurobiol. 2000 Apr;20(2):183-96. doi: 10.1023/a:1007045605751.
Abstract
- The fluid homeostasis of the brain depends both on the endothelial blood-brain barrier and on the epithelial blood-cerebrospinal fluid (CSF) barrier located at the choroid plexuses and the outer arachnoid membrane. 2. The brain has two fluid environments: the brain interstitial fluid, which surrounds the neurons and glia, and the CSF, which fills the ventricles and external surfaces of the central nervous system. 3. CSF acts as a fluid cushion for the brain and as a drainage route for the waste products of cerebral metabolism. 4. Recent findings suggest that CSF may also act as a "third circulation" conveying substances secreted into the CSF rapidly to many brain regions.
摘要
- 大脑的液体稳态既依赖于内皮血脑屏障，也依赖于位于脉络丛和蛛网膜外层的上皮血脑脊液（CSF）屏障。2. 大脑有两种液体环境：包围神经元和神经胶质的脑间质液，以及填充脑室和中枢神经系统外表面的脑脊液。3. 脑脊液充当大脑的液体缓冲垫，并作为大脑代谢废物的引流途径。4. 最近的研究结果表明，脑脊液还可能充当“第三循环”，将分泌到脑脊液中的物质迅速输送到许多脑区。
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