English J C, Meyer C, Lewey S M, Zinn C J
Dermatology Service, Evans Army Community Hospital, Fort Carson, Colorado, USA.
Cutis. 2000 Feb;65(2):107-9.
Although rare, metastatic hepatocellular carcinoma (HCC) presenting only to the mandible, gingiva, and nasal cavity in patients subsequently found to have primary HCC has been reported. In the age of transplantation, certain HCC patients may receive treatment with an orthotopic liver transplant. Due to the proclivity of HCC for early micrometastases, immunosuppressive therapy can induce significant metastatic lesions. Nasal mass obstruction, gingival lesions, or facial growths in this population must be considered metastatic until proven otherwise.
虽然罕见，但已有报道称，在随后被发现患有原发性肝细胞癌（HCC）的患者中，转移性HCC仅表现于下颌骨、牙龈和鼻腔。在移植时代，某些HCC患者可能接受原位肝移植治疗。由于HCC易于早期发生微转移，免疫抑制治疗可诱发显著的转移病灶。在未得到其他证实之前，必须将该人群中的鼻肿物阻塞、牙龈病变或面部肿物视为转移性病变。
