Otellin V A
Zh Vopr Neirokhir Im N N Burdenko. 1999 Oct-Dec(4):32-6; discussion 36-7.
The paper summarizes the results of long-term studies made by the Department of Morphology, Institute of Experimental Medicine, Russian Academy of Medical Sciences, and the data available in the literature on the problems of neurografting and histogenesis of nervous tissue in the human prenatal development. It presents data on the conditions that most favourably affect the acceptance and development of neurografts, the integration of their cell elements with the recipient's brain, and the correction of dysfunctions. Emphasis is laid on the choice of a donor's material, the modes of its treatment and insertion, on the determination of grafting sites and scope, on immunosuppression and postoperative drug provision.
本文总结了俄罗斯医学科学院实验医学研究所形态学系长期研究的结果,以及文献中关于人类产前发育中神经移植和神经组织组织发生问题的现有数据。文中介绍了最有利于神经移植物接受和发育、其细胞成分与受体大脑整合以及功能障碍矫正的条件。重点阐述了供体材料的选择、处理和植入方式、移植部位和范围的确定、免疫抑制和术后药物供应。