Gezen F, Ziyal I M, Baysefer A, Kahraman S, Ciklatekerlioglu O
Department of Neurosurgery, The Abant Izzet Baysal University, Düzce School of Medicine, Turkey.
Surg Neurol. 2000 Jan;53(1):61-3. doi: 10.1016/s0090-3019(99)00200-1.
Metastasis of a paraganglioma (PRG) to the calvarium is very rare. In this paper, the case of a 25-year-old male with metastasis of a PRG to the frontoparietal bone is described.
The patient presented with bulging on the left side of the head, headache, and weight loss. Magnetic resonance imaging (MRI) revealed a mass lesion in the left frontoparietal region that had destroyed both the external and internal table of the bone, extending under the skin and above the dura mater. After a frontoparietal craniotomy the tumor was removed totally. Histopathological examination revealed the "Zellballen," which are pathognomonic for a PRG. Systemic examination and radiological investigation revealed no primary tumor source.
Metastasis of a PRG to the calvarium is possible; radical removal of the tumor will provide a cure.
副神经节瘤（PRG）转移至颅骨极为罕见。本文描述了一例25岁男性PRG转移至额顶骨的病例。
患者出现头部左侧隆起、头痛及体重减轻症状。磁共振成像（MRI）显示左额顶区有一肿块，已破坏颅骨内外板，延伸至皮下及硬脑膜上方。经额顶开颅术后，肿瘤被完全切除。组织病理学检查发现了“Zellballen”，这是PRG的特征性表现。全身检查和影像学检查未发现原发肿瘤来源。
PRG可转移至颅骨；肿瘤的根治性切除可实现治愈。
