Tomita H, Yamashita H, Tamaki N
Department of Neurosurgery, Kobe National Hospital.
No Shinkei Geka. 1996 Nov;24(11):1045-8.
We report a case of malignant paraganglioma with intracranial metastasis. A 26-year-old man presented with leg pain. On admission a metastatic bone tumor was found. General examination revealed metastatic lesions in the lung, liver, orbits, ethmoid sinus, anterior mediastinum, and brain. An MRI of the head showed multiple lesions in the skull bone and intracranial space. A biopsy was performed on the right temporal tumor, resulting in a diagnosis of malignant paraganglioma. The tumor origin could not be determined. The tumor resection was not indicated because of multiple metastasis. Both chemotherapy and radiotherapy were given to the patient, but a satisfactory outcome was not obtained.
我们报告一例伴有颅内转移的恶性副神经节瘤。一名26岁男性因腿痛就诊。入院时发现有转移性骨肿瘤。全身检查发现肺部、肝脏、眼眶、筛窦、前纵隔和脑部有转移病灶。头部磁共振成像(MRI)显示颅骨和颅内有多个病灶。对右侧颞部肿瘤进行了活检,结果诊断为恶性副神经节瘤。肿瘤起源无法确定。由于存在多处转移,未行肿瘤切除术。对该患者进行了化疗和放疗,但未获得满意疗效。