Ringbaek T J, Brøndum E, Hemmingsen L, Lybeck K, Nielsen D, Andersen C, Lange P
Medicinsk klinik I, H:S Bispebjerg Hospital.
Ugeskr Laeger. 2000 Jan 24;162(4):498-501.
Several studies of patients with chronic obstructive pulmonary disease (COPD) have shown that pulmonary rehabilitation three to seven times a week improves exercise performance and well being. This study investigates feasibility, effect and economic aspects of a programme consisting of two sessions a week. Twenty-four patients were randomized to rehabilitation and twenty-one to placebo. In an outpatient setting patients were assigned to an eight-week programme of exercise plus education twice a week (Exercise group) or conventional community cares (Placebo group). Seven patients did not complete the rehabilitation. The characteristics of the thirty-eight COPD patients at baseline (mean +/- SD): forced expiratory volume in one second (FEV-1) 1.1 +/- 0.4 L, six-minute walk distance (6MWD) 413 +/- 75 m. Rehabilitation resulted in an insignificant improvement in well being and the 6MWD (29 m ¿95% confidence interval: -8-66 m¿. Rehabilitation session twice a week for eight weeks had no effect in patients with moderate COPD.
多项针对慢性阻塞性肺疾病（COPD）患者的研究表明，每周进行三至七次肺部康复可改善运动能力和健康状况。本研究调查了每周进行两次疗程的项目的可行性、效果和经济方面。24名患者被随机分配至康复组，21名被分配至安慰剂组。在门诊环境中，患者被分配至一个为期八周的项目，即每周进行两次运动加教育（运动组）或接受常规社区护理（安慰剂组）。7名患者未完成康复。38名COPD患者基线时的特征（均值±标准差）：一秒用力呼气量（FEV-1）为1.1±0.4升，六分钟步行距离（6MWD）为413±75米。康复对健康状况和6MWD的改善不显著（29米，95%置信区间：-8至66米）。对中度COPD患者而言，每周进行两次、为期八周的康复疗程没有效果。
