Elliott Mercedes, Watson Carol, Wilkinson Eve, Musk Arthur W, Lake Fiona R
Physiotherapy Department, Fremantle Hospital, Western Australia, Australia.
Respirology. 2004 Aug;9(3):345-51. doi: 10.1111/j.1440-1843.2004.00595.x.
Pulmonary rehabilitation in patients with COPD has been shown to be beneficial but the optimal setting is not known. In the present study, the efficacy of a short-term community-based exercise programme was compared with a standard hospital outpatient programme. Additionally, the usefulness of community or home programmes in maintaining improvements in the longer term was studied.
Forty-three patients with moderate to severe COPD were randomized to one of the following three groups: a 3-month hospital programme then a 9 month home programme (Hospital/Home); a 3-month hospital programme then a 9-month community programme (Hospital/Community); or a 12-month community programme (Community/Community). The initial 3-month programme was analysed by comparing the Hospital group (Hospital/Home plus Hospital/Community) with the Community group (Community/Community). Six-minute walking distance (6MWD), quality of life (Guyatt chronic respiratory disease questionnaire, CRQ) and lung function were measured at 0, 3, 6 and 12 months and results were analysed using the Wilcoxon rank sum test.
At 3 months, there was a significant improvement from baseline in 6MWD in the Hospital group (81.3 +/- 18.3 m, P < 0.05, anova) but not the Community group (14.4 +/- 28.5 m, not significant). The difference between the groups was not significant (P = 0.058). At 3 months, there was a significant improvement in quality of life in the Hospital group (CRQ +16.3 +/- 3.1, P < 0.01, anova) and in the Community group (CRQ +10.2 +/- 4.9, P < 0.05, anova) but the difference between the groups was not significant. Following the initial 3-month programme, the dropout rate was high overall (73% by 12 months), and therefore data from the maintenance programme could not be analysed.
A 3-month community-based exercise programme for patients with COPD did not improve 6MWD. The long-term retention rates in the programmes were poor.
慢性阻塞性肺疾病(COPD)患者的肺康复已被证明是有益的,但最佳方案尚不清楚。在本研究中,将短期社区运动计划的疗效与标准医院门诊计划进行了比较。此外,还研究了社区或家庭计划在长期维持改善方面的作用。
43例中重度COPD患者被随机分为以下三组之一:3个月医院计划加9个月家庭计划(医院/家庭);3个月医院计划加9个月社区计划(医院/社区);或12个月社区计划(社区/社区)。通过比较医院组(医院/家庭加医院/社区)和社区组(社区/社区)来分析最初的3个月计划。在0、3、6和12个月时测量6分钟步行距离(6MWD)、生活质量(盖亚特慢性呼吸道疾病问卷,CRQ)和肺功能,并使用Wilcoxon秩和检验分析结果。
3个月时,医院组的6MWD较基线有显著改善(81.3±18.3米,P<0.05,方差分析),而社区组无改善(14.4±28.5米,无显著性差异)。两组之间的差异无显著性(P = 0.058)。3个月时,医院组的生活质量有显著改善(CRQ +16.3±3.1,P<0.01,方差分析),社区组也有改善(CRQ +10.2±4.9,P<0.05,方差分析),但两组之间的差异无显著性。在最初的3个月计划之后,总体脱落率很高(到12个月时为73%),因此无法分析维持计划的数据。
针对COPD患者的3个月社区运动计划并未改善6MWD。这些计划的长期保留率较差。