剥脱综合征患者眼部前囊膜层发育的电子显微镜研究
Electron microscopic study on the development of precapsular layer in eyes with exfoliation syndrome.
作者信息
Zhang X, Khalil A K, Kubota T, Inomata H
机构信息
Department of Ophthalmology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
出版信息
Jpn J Ophthalmol. 2000 Jan-Feb;44(1):9-14. doi: 10.1016/s0021-5155(99)00175-6.
PURPOSE
To search for a pathogenic mechanism for the formation of the precapsular layer on the anterior lens surface in pre-exfoliative eyes.
METHODS
We examined anterior lens capsules obtained during surgery from 38 patients (control, 16; exfoliation suspect, 10; exfoliation, 12) by transmission electron microscopy.
RESULTS
A precapsular layer was found in 5 of 16 controls and 7 of 10 exfoliation suspects. It was composed mainly of microfibrils 5-8 nm in diameter. Degenerated zonular fragments were occasionally found interspersed in, and sometimes merged with microfibrils of the precapsular layer.
CONCLUSION
Zonular fibers might contribute to the formation of the precapsular layer in pre-exfoliation stages.
目的
探寻剥脱前期眼晶状体前表面前囊膜层形成的致病机制。
方法
我们通过透射电子显微镜检查了38例患者手术中获取的晶状体前囊膜（对照组16例；疑似剥脱组10例；剥脱组12例）。
结果
在16例对照组中有5例发现前囊膜层，10例疑似剥脱组中有7例发现。其主要由直径5 - 8纳米的微原纤维组成。偶尔发现退化的悬韧带碎片散布其中，有时与前囊膜层的微原纤维融合。
结论
悬韧带纤维可能在剥脱前期阶段促成前囊膜层的形成。
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