Rosti L, Cerini E, Festa P, Miola A, Brunelli V, Frigiola A
Cardiologia/Cardiochirurgia Pediatrica, Centro "E. Malan", Ospedale San Donato, San Donato Milanese, Milano, Italy.
J Endocrinol Invest. 2000 Jan;23(1):28-30. doi: 10.1007/BF03343672.
Recent studies have suggested the beneficial effects of GH treatment in patients with dilated cardiomyopathy. We have treated with recombinant human growth hormone (rhGH) a 6-year-old female with a complex congenital heart defect (severe tricuspid hypoplasia and malposition of the great arteries), who developed a progressive dilated cardiomyopathy of unknown etiology. rhGH treatment (0,1 U/kg/day, for 3 months) did not improve cardiac function, nor clinical symptoms, although we have no clear explanations for this. However, a trial with rhGH may be offered to children with dilated cardiomyopathy and waiting for heart transplantation.
近期研究表明生长激素治疗对扩张型心肌病患者有益。我们用重组人生长激素（rhGH）治疗了一名6岁患有复杂先天性心脏缺陷（严重三尖瓣发育不全和大动脉位置异常）的女性患者，该患者出现了病因不明的进行性扩张型心肌病。rhGH治疗（0.1 U/kg/天，持续3个月）并未改善心脏功能和临床症状，尽管我们对此尚无明确解释。然而，对于等待心脏移植的扩张型心肌病患儿，可考虑进行rhGH试验性治疗。
