Clark R P, Preston T D, Gordon-Nesbitt D C, Malka S, Sinclair L
J Hyg (Lond). 1976 Dec;77(3):321-5. doi: 10.1017/s0022172400055674.
We have assessed the effect of house-cleaning procedures on changes in airborne dust and bacteria counts and correlated these with respiratory function tests in 14 children with bronchial asthma who were known to have developed attacks at home, and who had positive skin tests to house dust and the house-dust mite. We have demonstrated that after cleaning procedures a positive and statistically significant correlation exists between the increase in the numbers of small particles, 2 mum. and less in diameter, in the environment, and reduction in mean peak flow. This indicates that particles of this size penetrate the bronchial tree and are the causative factor in the genesis of bronchospasm.
我们评估了房屋清洁程序对空气中灰尘和细菌数量变化的影响，并将其与14名支气管哮喘儿童的呼吸功能测试结果相关联。这些儿童已知在家中会发作哮喘，且对屋尘和屋尘螨的皮肤试验呈阳性。我们已经证明，清洁程序后，环境中直径2微米及更小的小颗粒数量增加与平均呼气峰流速降低之间存在正相关且具有统计学意义。这表明这种大小的颗粒可穿透支气管树，是支气管痉挛发生的致病因素。
