Sarsfield J K
Arch Dis Child. 1974 Sep;49(9):711-5. doi: 10.1136/adc.49.9.711.
The aetiological importance of the house-dust mite, sp., was examined in 133 asthmatic children referred to hospital. Evidence of sensitization to this allergen from positive skin tests and the presence of circulating specific IgE was found in the majority of these children and sensitization often began in the preschool years. studies of specific IgE levels were found to bear a close relation to nasal provocation tests and probably have an important place in the identification of offending allergens in the paediatric patient. Ecological studies of the house-dust mite revealed its common occurrence in domestic environments, especially in the bed and bedroom. The mites were not found in hospital beds and only low levels of infestation were found in perambulators and cots and in residential schools for `delicate' children. The findings stress the major importance of this allergen in the causation of childhood asthma.
对133名转诊至医院的哮喘儿童进行了研究，以探讨屋尘螨（ 种）在病因学上的重要性。在这些儿童中的大多数身上，通过阳性皮肤试验发现了对这种过敏原致敏的证据以及循环特异性IgE的存在，并且致敏通常始于学龄前。研究发现，特异性IgE水平与鼻激发试验密切相关，可能在识别儿科患者的致病过敏原方面具有重要地位。对屋尘螨的生态学研究表明，它在家庭环境中普遍存在，尤其是在床上和卧室里。在医院的病床中未发现螨虫，在婴儿车、婴儿床以及为“体弱”儿童设立的寄宿学校中仅发现低水平的螨虫感染。这些发现强调了这种过敏原在儿童哮喘病因中的主要重要性。
