锝-99m（V）二巯基丁二酸闪烁扫描术在骨闪烁扫描术中对超级骨显像评估中的作用。
The role of Tc-99m (V) DMSA scintigraphy in the evaluation of superscan on bone scintigraphy.
作者信息
Yüksel D, Ilgan S, Arslan N, Uğur O, Oztürk E, Bayhan H
机构信息
Pamukkale University Medical Faculty, Department of Nuclear Medicine, Denizli, Turkey.
出版信息
Clin Nucl Med. 2000 Mar;25(3):193-6. doi: 10.1097/00003072-200003000-00008.
PURPOSE
This study evaluated the biodistribution of Tc-99m (V) DMSA in patients with superscans on bone imaging and defined its role in differentiating the underlying cause.
METHODS
Nine patients (five with metastatic and four with metabolic bone disease) with classical superscans were entered into the study. All patients had the necessary radiologic and biochemical studies and a final diagnosis was reached accordingly. Tc-99m (V) DMSA scintigraphy was performed 1 week after Tc-99m MDP whole-body bone imaging.
RESULTS
In four of five patients with widespread skeletal metastases, Tc-99m (V) DMSA scan showed diffusely increased bone uptake. In the remaining patient, the Tc-99m (V) DMSA scan showed a normal distribution pattern. All patients with metabolic bone disease had increased bone uptake on Tc-99m (V) DMSA scans.
CONCLUSION
Tc-99m (V) DMSA shows increased bone uptake in patients having a superscan appearance in metastatic or metabolic bone disease. Tc-99m (V) DMSA imaging may play a role in the evaluation of patients with equivocal bone scan findings for a superscan.
目的
本研究评估了锝-99m（V）二巯基丁二酸（Tc-99m（V）DMSA）在骨显像出现超级骨显像表现的患者中的生物分布，并明确其在鉴别潜在病因中的作用。
方法
9例具有典型超级骨显像表现的患者（5例为骨转移瘤，4例为代谢性骨病）纳入本研究。所有患者均进行了必要的影像学和生化检查，并据此得出最终诊断。在锝-99m亚甲基二膦酸盐（Tc-99m MDP）全身骨显像后1周进行Tc-99m（V）DMSA闪烁显像。
结果
5例广泛骨转移患者中有4例，Tc-99m（V）DMSA扫描显示骨摄取弥漫性增加。其余1例患者，Tc-99m（V）DMSA扫描显示分布正常。所有代谢性骨病患者的Tc-99m（V）DMSA扫描均显示骨摄取增加。
结论
Tc-99m（V）DMSA在骨转移瘤或代谢性骨病出现超级骨显像表现的患者中显示骨摄取增加。Tc-99m（V）DMSA显像可能在对骨扫描结果不明确的超级骨显像患者的评估中发挥作用。
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