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The oligomeric distribution of SecYEG is altered by SecA and translocation ligands.
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3
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4
Binding, activation and dissociation of the dimeric SecA ATPase at the dimeric SecYEG translocase.
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Preprotein translocation by a hybrid translocase composed of Escherichia coli and Bacillus subtilis subunits.
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Interaction between SecA and SecYEG in micellar solution and formation of the membrane-inserted state.
Biochemistry. 1998 Jan 6;37(1):201-10. doi: 10.1021/bi972105t.
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Electron microscopic visualization of asymmetric precursor translocation intermediates: SecA functions as a dimer.
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8
SecYEG and SecA are the stoichiometric components of preprotein translocase.
J Biol Chem. 1995 Aug 25;270(34):20106-11. doi: 10.1074/jbc.270.34.20106.
9
A single amino acid substitution in SecY stabilizes the interaction with SecA.
J Biol Chem. 1999 Aug 20;274(34):23868-74. doi: 10.1074/jbc.274.34.23868.
10
In vivo cross-linking of the SecA and SecY subunits of the Escherichia coli preprotein translocase.
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Dual recognition of multiple signals in bacterial outer membrane proteins enhances assembly and maintains membrane integrity.
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Structural basis of BAM-mediated outer membrane β-barrel protein assembly.
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3
Determination of the Oligomeric State of SecYEG Protein Secretion Channel Complex Using in Vivo Photo- and Disulfide Cross-linking.
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The TatC component of the twin-arginine protein translocase functions as an obligate oligomer.
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Mechanisms of Rose Bengal inhibition on SecA ATPase and ion channel activities.
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Glycolipozyme MPIase is essential for topology inversion of SecG during preprotein translocation.
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7
Dynamic structure of the translocon SecYEG in membrane: direct single molecule observations.
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Structural characterization of the complex of SecB and metallothionein-labeled proOmpA by cryo-electron microscopy.
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9
A single copy of SecYEG is sufficient for preprotein translocation.
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本文引用的文献
1
Preprotein translocation by a hybrid translocase composed of Escherichia coli and Bacillus subtilis subunits.
J Bacteriol. 1999 Nov;181(22):7021-7. doi: 10.1128/JB.181.22.7021-7027.1999.
2
Functional identification of the product of the Bacillus subtilis yvaL gene as a SecG homologue.
J Bacteriol. 1999 Mar;181(6):1786-92. doi: 10.1128/JB.181.6.1786-1792.1999.
3
The Sec system.
Curr Opin Microbiol. 1998 Apr;1(2):216-22. doi: 10.1016/s1369-5274(98)80014-3.
4
Membrane deinsertion of SecA underlying proton motive force-dependent stimulation of protein translocation.
EMBO J. 1999 Feb 15;18(4):1049-58. doi: 10.1093/emboj/18.4.1049.
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The bacterial SecY/E translocation complex forms channel-like structures similar to those of the eukaryotic Sec61p complex.
J Mol Biol. 1999 Jan 29;285(4):1789-800. doi: 10.1006/jmbi.1998.2413.
6
Translocase-bound SecA is largely shielded from the phospholipid acyl chains.
Biochemistry. 1998 Sep 1;37(35):12261-8. doi: 10.1021/bi9809021.
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Mass Measurement in the Scanning Transmission Electron Microscope: A Powerful Tool for Studying Membrane Proteins.
J Struct Biol. 1998;121(2):219-30. doi: 10.1006/jsbi.1997.3953.
8
BiP maintains the permeability barrier of the ER membrane by sealing the lumenal end of the translocon pore before and early in translocation.
Cell. 1998 Mar 20;92(6):747-58. doi: 10.1016/s0092-8674(00)81403-8.
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Bacterial preprotein translocase: mechanism and conformational dynamics of a processive enzyme.
Mol Microbiol. 1998 Feb;27(3):511-8. doi: 10.1046/j.1365-2958.1998.00713.x.
10
Sec-dependent membrane protein biogenesis: SecYEG, preprotein hydrophobicity and translocation kinetics control the stop-transfer function.
EMBO J. 1998 Feb 2;17(3):696-705. doi: 10.1093/emboj/17.3.696.
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