Holmberg M, Holmberg S, Herlitz J
Department of Cardiology, Sahlgrenska University Hospital, SE-413 45, Göteborg, Sweden.
Resuscitation. 2000 Mar;44(1):7-17. doi: 10.1016/s0300-9572(99)00155-0.
The chance of survival from ventricular fibrillation (VF) is up to ten times higher than those with other cardiac arrest rhythms. To calculate the effect of out-of-hospital resuscitation organisations on survival, it is necessary to know the percentage of cardiac arrest patients initially in VF and the relationship between delay time to defibrillation and survival.
To study the incidence of VF at the time of cardiac arrest and on first ECG, the duration of VF and the relation between time to defibrillation and survival.
The Swedish Cardiac Arrest Registry has collected standardised reports on out-of-hospital cardiac arrests from ambulance organisations in Sweden, serving 60% of the Swedish population.
In 14065 cases of out-of-hospital cardiac arrest collected between 1990 and 1995, resuscitation was attempted in 10966 cases.
The first ECG showed VF in 43% of all patients. The incidence of VF at the time of cardiac arrest was estimated to be 60-70% in all patients and 80-85% in the cases with probable heart disease.
The estimated disappearance rate of VF was slow. Thirty minutes after collapse approximately 40% of the patients were in VF.
Overall survival to 1 month was only 1.6% for patients with non-shockable rhythms and 9.5% for patients found in VF. With increasing time to defibrillation, the survival rate fell rapidly from approximately 50% with a minimal delay to 5% at 15 min.
This study suggests a high initial incidence of VF among out-of-hospital cardiac arrest patients and a slow rate of transformation into a non-shockable rhythm. The survival rate with very short delay times to defibrillation was approximately 50%, but decreased rapidly as the delay increased.
心室颤动(VF)患者的存活几率比其他心脏骤停节律患者高出多达十倍。为了计算院外复苏组织对存活的影响,有必要了解最初处于VF的心脏骤停患者的百分比以及除颤延迟时间与存活之间的关系。
研究心脏骤停时及首次心电图检查时VF的发生率、VF持续时间以及除颤时间与存活之间的关系。
瑞典心脏骤停登记处收集了来自瑞典救护车组织的院外心脏骤停标准化报告,这些组织服务于60%的瑞典人口。
在1990年至1995年期间收集的14065例院外心脏骤停病例中,10966例尝试进行了复苏。
所有患者中43%的首次心电图显示为VF。据估计,所有患者心脏骤停时VF的发生率为60 - 70%,可能患有心脏病的患者中为80 - 85%。
估计VF消失速度缓慢。心脏骤停30分钟后,约40%的患者仍处于VF状态。
非可电击节律患者1个月的总体存活率仅为1.6%,VF患者为9.5%。随着除颤时间的增加,存活率从延迟最短时的约50%迅速下降至15分钟时的5%。
本研究表明,院外心脏骤停患者中VF的初始发生率较高,转变为非可电击节律的速度较慢。除颤延迟时间极短时的存活率约为50%,但随着延迟增加迅速下降。