关节腔内注射皮质类固醇时滑膜液抽吸的重要性。
Importance of synovial fluid aspiration when injecting intra-articular corticosteroids.
作者信息
Weitoft T, Uddenfeldt P
机构信息
Section of Rheumatology, Department of Internal Medicine, County Hospital Gävle-Sandviken, S-801 87 Gävle, Sweden.
出版信息
Ann Rheum Dis. 2000 Mar;59(3):233-5. doi: 10.1136/ard.59.3.233.
OBJECTIVE
The aim of this prospective study was to find if a complete synovial fluid aspiration before injecting intra-articular corticosteroids influences the treatment result.
METHODS
The study was performed in 147 patients with rheumatoid arthritis (RA). One hundred and ninety one knees with synovitis were randomised to arthrocentesis (n=95) or no arthrocentesis (n = 96) before 20 mg triamcinolone hexacetonide was injected. The duration of effect was followed up for a period of six months. All patients were instructed to contact the rheumatology department if signs and symptoms from the treated knee recurred. If arthritis could be confirmed by a clinical examination a relapse was noted.
RESULTS
There was a significant reduction of relapse in the arthrocentesis group (p = 0.001).
CONCLUSION
The study shows that aspiration of synovial fluid can reduce the risk for arthritis relapse when treating RA patients with intra-articular corticosteroids. It is concluded that arthrocentesis shall be included in the intra-articular corticosteroid injection procedure.
目的
本前瞻性研究旨在探讨在关节腔内注射皮质类固醇之前进行完全的关节液抽吸是否会影响治疗效果。
方法
对147例类风湿关节炎（RA）患者进行了研究。将191个患有滑膜炎的膝关节随机分为关节穿刺组（n = 95）和未进行关节穿刺组（n = 96），然后在两组膝关节内注射20mg己曲安奈德。对治疗效果持续随访6个月。所有患者均被告知，如果治疗的膝关节出现复发的体征和症状，需联系风湿科。如果通过临床检查能够确诊关节炎，则记录为复发。
结果
关节穿刺组的复发率显著降低（p = 0.001）。
结论
该研究表明，在用关节腔内皮质类固醇治疗RA患者时，抽吸关节液可降低关节炎复发的风险。得出的结论是，关节穿刺应纳入关节腔内皮质类固醇注射操作过程中。
Zotero 插件