Persson G R, Falk H, Laurell L
Department of Periodontics, Regional Clinical Dental Research Center, University of Washington, Seattle 98195, USA.
J Clin Periodontol. 2000 Feb;27(2):104-8. doi: 10.1034/j.1600-051x.2000.027002104.x.
Intra-bony defects remain a significant therapeutic problem in periodontal therapy. Various non-surgical and surgical treatment modalities are being used. The long-term stability following treatment of intra-bony defects is poorly documented.
To assess changes in intra-bony defects after either osseous surgery or open flap debridement in combination with grafting procedures with demineralized freeze-dried bone allografts (DFDBA).
Pre- and post-surgical computer digitized images of intra-oral radiographs from 60 patients who had received periodontal surgery to manage intrabony defects were analyzed by linear measurements.
36 patients were treated with osseous surgery and 24 had received flap procedures and grafting with DFDBA. Post-surgical radiographs were obtained on average after 4.8 years (SD+/-2.8) and after 9.6 years (SD+/-3.6). A minor mean bone fill of 0.0 mm (SD+/-0.8) for osseous surgery sites and 0.5 mm (SD+/-0.9) for DFDBA sites, was noticed, but this gain was within the margin of measurement errors. Osseous surgery and modified Widman flap procedures with DFDBA resulted in crestal resorption, on average 1.7 mm (SD+/-1.5) and 1.5 mm (SD+/-1.5) and remaining mean defect depth of 2.0 mm (SD+/-1.4) and 2.5 mm (SD+/-1.6), respectively.
Bone changes following bone graft procedures with DFDBA did not differ from those following osseous surgery, and neither procedure resulted in defect resolution with bone fill. It was also concluded that over the study period, stable treatment results were obtained as a result of both osseous surgery and modified Widman flap procedures with adjunct DFDBA.
骨内缺损仍是牙周治疗中的一个重大治疗难题。目前正在使用各种非手术和手术治疗方法。骨内缺损治疗后的长期稳定性记录较少。
评估骨手术或开放瓣清创联合脱矿冻干骨同种异体移植物(DFDBA)移植术后骨内缺损的变化。
对60例接受牙周手术治疗骨内缺损患者的术前和术后口腔X光数字化图像进行线性测量分析。
36例患者接受了骨手术,24例接受了瓣手术并使用DFDBA移植。术后X光片平均在4.8年(标准差±2.8)和9.6年(标准差±3.6)后获得。骨手术部位平均骨填充量为0.0毫米(标准差±0.8),DFDBA部位为0.5毫米(标准差±0.9),但这种增加在测量误差范围内。骨手术和使用DFDBA的改良Widman瓣手术导致牙槽嵴吸收,平均分别为1.7毫米(标准差±1.5)和1.5毫米(标准差±1.5);剩余平均缺损深度分别为2.0毫米(标准差±1.4)和2.5毫米(标准差±1.6)。
使用DFDBA进行骨移植术后的骨变化与骨手术后的变化没有差异,两种方法均未通过骨填充实现缺损修复。研究还得出结论,在研究期间,骨手术和使用DFDBA的改良Widman瓣手术均获得了稳定的治疗效果。