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羟基磷灰石与β-磷酸三钙复合移植物治疗骨内牙周缺损的临床评价:一项临床影像学研究。

Clinical evaluation of hydroxyapatite and β-tricalcium phosphate composite graft in the treatment of intrabony periodontal defect: A clinico-radiographic study.

作者信息

Bansal Rajat, Patil Sudhir, Chaubey Krishna Kumar, Thakur Rajesh Kumar, Goyel Purnita

机构信息

Department of Periodontics, Kothiwal Dental College and Research Centre, Moradabad, Uttar Pradesh, India.

出版信息

J Indian Soc Periodontol. 2014 Sep;18(5):610-7. doi: 10.4103/0972-124X.142455.

Abstract

BACKGROUND AND OBJECTIVE

Hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP) grafts have shown to be effective in promoting the clinical signs of periodontal regeneration in intrabony defects. The aim of our study was to clinically and radiographically evaluate the efficacy of HA and β-TCP composite bone graft material in the treatment of intrabony three-wall defect.

MATERIALS AND METHODS

Twenty patients participated in this study. Interproximal bony defects were surgically treated with a combination of HA-βTCP (biphasic calcium phosphate). Changes in clinical parameters such as gingival status, probing pocket depth, clinical attachment, and radiographic estimation of the amount of bone fill were evaluated after 6 months postoperatively.

STATISTICAL ANALYSIS USED

Student's "t" test.

RESULTS

This treatment modality resulted in significant pocket depth reduction and clinical attachment gain which were observed to be 2.938 mm (47.04%) and 3.188 mm (29.09%), respectively. The defect fill as seen radiographically was 3.204 mm (63.195%). All the differences were highly significant and in favor of postoperative group.

CONCLUSION

The results of this study suggest that HA-βTCP (biphasic calcium phosphate) provides an added regenerative effect in promoting the clinical resolution of intrabony three-wall defects in patients with periodontitis.

摘要

背景与目的

羟基磷灰石(HA)和β-磷酸三钙(β-TCP)移植物已被证明在促进骨内缺损的牙周再生临床体征方面有效。本研究的目的是从临床和影像学角度评估HA和β-TCP复合骨移植材料治疗骨内三壁缺损的疗效。

材料与方法

20名患者参与了本研究。用HA-βTCP(双相磷酸钙)联合手术治疗邻间骨缺损。术后6个月评估临床参数的变化,如牙龈状况、探诊袋深度、临床附着以及骨填充量的影像学评估。

所用统计分析方法

学生“t”检验。

结果

这种治疗方式导致探诊袋深度显著降低,临床附着增加,分别为2.938毫米(47.04%)和3.188毫米(29.09%)。影像学显示的缺损填充为3.204毫米(63.195%)。所有差异均具有高度显著性,且有利于术后组。

结论

本研究结果表明,HA-βTCP(双相磷酸钙)在促进牙周炎患者骨内三壁缺损的临床愈合方面具有额外的再生作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb0e/4239751/c42d3e5194d5/JISP-18-610-g001.jpg

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