Ogundele M O
Department of Immunology, Georg-August University, Kreuzbergring 57, Göttingen, D-37075, Germany.
Cell Biol Int. 1999;23(8):585-8. doi: 10.1006/cbir.1999.0425.
Human milk stored over some period in vitro possesses certain cytotoxic properties, which require further studies. Cytolysis induced by stored human milk has now been further characterized, using rabbit red blood cells as targets, to determine the contribution of other components, particularly the complement system. Cytolysis was found to be temperature dependent, greatly enhanced by low concentrations of magnesium and calcium ions, but inhibited by moderate to excessive amounts of calcium ions, and by heating at 56 degrees C.
体外储存一段时间的人乳具有一定的细胞毒性特性，这需要进一步研究。现在，以兔红细胞为靶标，对储存人乳诱导的细胞溶解进行了进一步表征，以确定其他成分特别是补体系统的作用。发现细胞溶解与温度有关，低浓度的镁离子和钙离子可大大增强细胞溶解，但中度至过量的钙离子以及在56℃加热会抑制细胞溶解。
