Lohff B
Abteilung Medizingeschichte, Ethik und Theoriebildung in der Medizin der MHH, Hannover.
Sudhoffs Arch. 1999;83(2):131-51.
Not until 60 years after 1899 Otto Frank's mathematical formulation of the volume-pressure diagram and his concept of the mechanism of the cardiac work of the left ventricle cardio-physiologists began to rediscover Frank's work systematically. Frank's scientific development proves his constant commitment to and deep interest in understanding and analysing physiological problems mathematically. Consequently Frank worked on the quality and theory of physiological instruments and the problems of measurement, to calculate the influence in experimental research of the cardio-vascular system. Besides Frank's publications on different types of manometers his theory of "Windkessel" function as a model of the mechanics of the left ventricle and the different energies of the cardiac work are of importance even today, although we know only few details of his life as a pupil of Carl Ludwig and Carl von Voit and as a professor of physiology in Giessen and Munich.
直到1899年奥托·弗兰克对容积-压力图进行数学公式化表述并提出左心室心脏工作机制的概念60年后，心脏生理学家才开始系统地重新发现弗兰克的研究成果。弗兰克的科学发展证明了他始终致力于以数学方式理解和分析生理问题，并对其有着浓厚的兴趣。因此，弗兰克致力于生理仪器的质量和理论以及测量问题，以计算心血管系统实验研究中的影响。除了弗兰克关于不同类型压力计的出版物外，他的“风箱”功能理论作为左心室力学模型以及心脏工作的不同能量，即使在今天也很重要，尽管我们对他作为卡尔·路德维希和卡尔·冯·福伊特的学生以及在吉森和慕尼黑担任生理学教授的生活细节知之甚少。
